Fatal Flaws

Hardcover | May 15, 2012

byJay Ingram

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Most people have never heard of prions. Indeed, most are only barely aware of the diseases caused by them, except, perhaps, for mad cow disease. Yet prions are the stuff of a revolutionary science—a science that might lead to cures for some of humankind’s most devastating diseases.

Fatal Flaws is a scientific detective story about this elusive protein, starting with the discovery of kuru, a disease unique to New Guinea in the 1950s that baffled scientists and carried with it whispers of cannibalism. Kuru began a scientific stampede to seek out the agent of this mysterious disease—the prion—a misfolded protein whose existence some of the world’s top scientists still find difficult to accept. Today, the subject of prions remains controversial, yet the proteins might promise new treatments for some of the most intractable brain diseases, ones that affect millions around the planet, including Parkinson’s, ALS and Alzheimer’s.

In Fatal Flaws, Jay Ingram unties a complicated interweaving of biology, medicine, human tragedy, surprise and disbelief in the world of prions, and he unravels some of history’s most stunning revelations about disease, the brain and infection.

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Most people have never heard of prions. Indeed, most are only barely aware of the diseases caused by them, except, perhaps, for mad cow disease. Yet prions are the stuff of a revolutionary science—a science that might lead to cures for some of humankind’s most devastating diseases.Fatal Flaws is a scientific detective story about this ...

JAY INGRAM was the host of Discovery Channel Canada’sDaily Planetfrom the first episode until June 2011. Prior to joining Discovery, Ingram hosted CBC Radio’s national science show,Quirks & Quarks. He has received the Sandford Fleming Medal from the Royal Canadian Institute, the Royal Society’s McNeil Medal for the Public Awareness of ...

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Format:HardcoverDimensions:272 pages, 9.41 × 7.24 × 1 inPublished:May 15, 2012Publisher:HarperCollinsLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1443412120

ISBN - 13:9781443412124

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