A Decade of HAART: The Development and Global Impact of Highly Active Antiretroviral Therapy

Hardcover | November 1, 2008

EditorJose M. Zuniga, Alan Whiteside, Amin Ghaziani

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Highly active antiretroviral therapy (HAART) is a therapeutic intervention developed by clinicians and researchers in order to fight the HIV pandemic. It has contributed to a significant reduction in AIDS-related mortality and allowed many previously bed-ridden patients to live healthier, moreproductive lives. Until the advent of HAART in 1996, a diagnosis of HIV infection was considered a death sentence. A decade later, the disease has been transformed into a serious, yet potentially manageable, medical condition for thousands of people living with HIV/AIDS in the developed world -almost overnight creating a generation of "HIV Survivors" - and forged a global movement to ensure that its Lazarus-like benefit reaches millions more in the developing world. This book reviews the achievements of HAART over the past decade, and explores the challenges that may arise in the future. It recounts key landmarks in the development and introduction of HAART from the perspective of clinicians, researchers, economists, sociologists, and public policy experts,including the co-discoverers of HIV, Luc Montagnier and Robert Gallo. It explores the evolution of the disease, the evolution of HIV treatment, and the economic, social, and public policy impacts of both HIV and the introduction of HAART.

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Highly active antiretroviral therapy (HAART) is a therapeutic intervention developed by clinicians and researchers in order to fight the HIV pandemic. It has contributed to a significant reduction in AIDS-related mortality and allowed many previously bed-ridden patients to live healthier, moreproductive lives. Until the advent of HAART...

Jose M. Zuniga is President/CEO of the International Association of Physicians in AIDS Care in Chicago, USA. Alan Whiteside is Director, Health and Economics and HIV/AIDS Research Division (HEARD) at the University of KwaZulu-Natal, Durban in South Africa. Amin Ghaziani is Cotsen Postdoctoral Fellow, Society of Fellows at Princeton Un...
Format:HardcoverDimensions:464 pages, 9.69 × 6.73 × 1.3 inPublished:November 1, 2008Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199225850

ISBN - 13:9780199225859

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Table of Contents

Luc Montagnier and Robert Gallo: Foreword1. Jose M Zuniga, Alan Whiteside, Amin Ghaziani and John G Bartlett: IntroductionA Decade of HAART: Trials, Tribulations, and Successes2. Jose M Zuniga and Amin Ghaziani: A world ravaged by a disease without HAART3. Michel D Kazatchkine and Lieve Fransen: Turning the world on its ear: defining milestones on the road to HAART4. Eduard J Beck and Rochelle P Walensky: Outcome and impact of 10 years of HAART5. Arry Dieudonne, James A McIntyre, Federica Freginese, Carla Giaqutinto and James M Oleske: Highly Active Anti-Retroviral Therapy in HIV-infected children: a decade laterHAART in High Human Development Countries6. Kathleen Glenday, Kathy Petoumenos, Matthew G Law and David A Cooper: Country review: Australia7. Marcelo J Wolff: Country review: Chile8. Eva Wolf and Hans Jaeger: Country review: Germany9. Renato Maserati: Country review: Italy10. Renslow Sherer: Country review: United States of America11. Frank J Palella Jr, Anne C Moorman, John T Brooks; John Phair, Lisa Jacobson, Roger Detels, Joseph Margolick and Charles Rinaldo: The HIV Outpatient Study (HOPS) and the Multicenter AIDS Cohort Study12. Dominique Costagliola: The French Hospital Database on HIV (FHDH) ANRS CO.413. Jens D Lundgren, Ole Kirk and Amanda Mocroft: EuroSIDA: A prospective observational study of chronic HIV infection 13-1 Across the European continent14. Huldrych F Gunthard and Bernard Hirschel: The Swiss HIV Cohort (SHCS)15. Mark Holodniy: The OPTIMA CohortHAART in Medium Human Development Countries16. Celso Ferreira Ramos-Filho and Cledy Eliana dos Santos: Country review: Brazil17. Zhang Fu-Jie, Ray Y Chen, Selina N Lo and Ma Ye: Country review: China18. Robin Wood and Des Martin: Country review: South Africa19. Praphan Phanuphak, Sanchai Chasombat and Jintanat Ananworanich: Country review: Thailand20. Mauro Schechter and Suely Hiromi Tuboi: Cohort studies in Brazil: Projet Praca Onze21. Kiat Ruxrungtham: The HIV Netherlands-Australia-Thailand research collaboration (HIVNAT)HAART in Low Human Development Countries22. Serena Koenig, Julia Carney, Peter Bendix and Jean William Pape: Country review: Haiti23. Erik J Schouten, Simon D Makombe, Anthony D Harries and Kelita Kamoto: Country review: Malawi24. Papa Salif Sow: Country review: Senegal25. Moses Sinkala and Benjamin H Chi: Country review: ZambiaFuture Challenges in the Next Decade of HAART26. Roger Paredes, Renslow Sherer and Bonaventura Clotet: Clinical challenges of lifetime HAART27. Stephanie Nixon and Nina Veenstra: Maintaining and developing health systems to sustain HAART28. Mario Roberto Dal Poz, Norbert Dreesch and Dingie van Rensburg: Redefining HIV/AIDS care delivery in the face of human resource scarcity29. Peter Piot, Julian Fleet and Siddharth Dube: Conclusion: closing the gap - one world, one standard