A History Of Modern Immunology: The Path Toward Understanding

Paperback | October 30, 2017

byZoltan A. Nagy

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A History of Modern Immunology: A Path Toward Understanding describes, analyzes, and conceptualizes several seminal events and discoveries in immunology in the last third of the 20th century, the era when most questions about the biology of the immune system were raised and also found their answers. Written by an eyewitness to this history, the book gives insight into personal aspects of the important figures in the discipline, and its data driven emphasis on understanding will benefit both young and experienced scientists. This book provides a concise introduction to topics including immunological specificity, antibody diversity, monoclonal antibodies, major histocompatibility complex, antigen presentation, T cell biology, immunological tolerance, and autoimmune disease. This broad background of the discipline of immunology is a valuable companion for students of immunology, research and clinical immunologists, and research managers in the pharmaceutical and biotechnology industries. Contains the history of major breakthroughs in immunology featured with authenticity and insider details Gives an insight into personal aspects of the players in the history of immunology Enables the reader to recognize and select data of heuristic value which elucidate important facets of the immune system Provides good examples and guidelines for the recognition and selection of what is important for the exploration of the immune system Gives clear separation of descriptive and interpretive parts, allowing the reader to distinguish between facts and analysis provided by the author

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A History of Modern Immunology: A Path Toward Understanding describes, analyzes, and conceptualizes several seminal events and discoveries in immunology in the last third of the 20th century, the era when most questions about the biology of the immune system were raised and also found their answers. Written by an eyewitness to this his...

From the Jacket

This book summarizes the major events in immunology during the 20thcentury, an era when most questions about the biology of the immune system were raised and also found their answers. Written by an eye witness, it provides a concise introduction to the following topics: immunological specificity, antibody diversity, monoclonal antibodi...

Dr. Nagy, a world-leading immunologist, previously held positions as Scientific Member of the Basel Institute of Immunology, Deputy Director of the Max-Planck-Institute for Biology in Tuebingen, Project Leader in Preclinical Research at Novartis in Basel and most recently as Department Head of Immunology at Hoffmann-La Roche in Nutley....

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Format:PaperbackDimensions:356 pages, 8.75 × 6.35 × 0.68 inPublished:October 30, 2017Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0128100737

ISBN - 13:9780128100738

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Extra Content

Table of Contents

Introductory Words about Science, Scientists, and Immunology

Part One: Pre-History with Far-reaching Consequences

1 The immunological revolution

Part Two: The History

2 A very special location: the basel institute for immunology

3 Immunological specificity

4 Monoclonal antibodies: the final proof for clonal selection

5 The first victory of molecular biology: mechanisms of the generation of antibody diversity

6 The major histocompatibility complex

7 Antigen processing and presentation

8 The intricate behaviour of t cells

9 Acquired immunological tolerance

10 Autoimmunity

Concluding Remarks