A Short History of the Drug Receptor Concept by C. PrA Short History of the Drug Receptor Concept by C. Pr

A Short History of the Drug Receptor Concept

byC. Pr

Hardcover | June 25, 2009

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The concept of specific receptors for drugs, hormones and transmitters lies at the very heart of biomedicine. This book is the first to consider the idea from its 19th century origins in the work of John Newport Langley and Paul Ehrlich, to its development of during the 20th century and its current impact on drug discovery in the 21st century.
CAY-RÜDIGER PRÜLL is Senior Lecturer in the History of Medicine at the University of Freiburg, Germany. Currently he is supervising projects on the history of pharmacology and on the history of German military medicine between 1914 and 1945. Between 2000 and 2003 he was Senior Research Associate at the University of Durham, UK, working...
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Title:A Short History of the Drug Receptor ConceptFormat:HardcoverDimensions:239 pages, 8.5 × 5.51 × 0.97 inPublished:June 25, 2009Publisher:Palgrave MacmillanLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0230554156

ISBN - 13:9780230554153

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Table of Contents

Introduction Paul Ehrlich and his Receptor Concept The Development of the Concept of Drug Receptors in the Physiological Research of J. N. Langley The Receptors and Scientific Pharmacology I: The Critics of the Receptor Idea and Alternative Theories of Drug Action, c. 1905-1935 The Receptors and Scientific Pharmacology II: The Critics of the Receptor Idea and Alternative Research Strands: The Transmitter Theory, c. 1905-1935 Quantitative Arguments for the Existence of Drug Receptors and the Development of the Receptor Occupancy Theory, c. 1910-1960 The Dual Adrenaline Receptor Theory of Raymond P. Ahlquist (1914-1983) and its Application in Drug Development between 1950 and 1970 The Emergence of Molecular Pharmacology Conclusions Archival Sources Bibliography