Actin-Binding Proteins and Disease by Cris dos RemediosActin-Binding Proteins and Disease by Cris dos Remedios

Actin-Binding Proteins and Disease

EditorCris dos Remedios

Hardcover | November 26, 2007

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There are scattered reports in the published literature citing relationships between actin, actin-binding proteins and disease. This volume brings this information together for the first time, with a focus on human disorders. The volume is relevant to a wide readership including cell biologists interested in understanding how structural and functional changes in proteins impact on the organism as a whole.
Title:Actin-Binding Proteins and DiseaseFormat:HardcoverDimensions:362 pages, 9.25 × 6.1 × 0.01 inPublished:November 26, 2007Publisher:Springer New YorkLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0387717471

ISBN - 13:9780387717470


Table of Contents

Overview of actin.- Actin Genetic Diseases.- Actin-binding drugs.- Filamentous actin as an autoantigen.- Actin Binding Protein Function and its Relation to Disease Pathology.- ADF/cofilin, actin dynamics and disease.- Gelsolin and disease.- Profilin and disease.- The roles of thymosin beta4 in cell migration and cell-to-cell signalling in disease.- Actin and actin binding proteins in cancer progression and metastasis.- Defects in actin and actin-binding proteins in leukocytes.- The role of PIP2 in actin, actin-binding proteins and disease.- Intracellular pathogens and the actin cytoskeleton.- Actin and its binding proteins in heart failure.