Advances in Alzheimer's and Parkinson's Disease: Insights, Progress, and Perspectives by Abraham FisherAdvances in Alzheimer's and Parkinson's Disease: Insights, Progress, and Perspectives by Abraham Fisher

Advances in Alzheimer's and Parkinson's Disease: Insights, Progress, and Perspectives

EditorAbraham Fisher, Maurizio Memo, Fabrizio Stocchi

Paperback | November 25, 2010

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This volume contains the proceedings of the 2005 ADPD conference and is unique in that it deals not only with issues related individually to Alzheimer's disease and Parkinson's disease, but also with the integration of these and other related diseases. The most up-to-date techniques and research findings are illustrated in this volume, which covering topics from immunology, neuroscience, and pharmacology to genetics and molecular biology. Possible future developments in the treatment of Alzheimer's and Parkinson's Diseases are also covered.
Title:Advances in Alzheimer's and Parkinson's Disease: Insights, Progress, and PerspectivesFormat:PaperbackDimensions:480 pagesPublished:November 25, 2010Publisher:Springer USLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1441944230

ISBN - 13:9781441944238

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Table of Contents

Clinical Features and Treatment of Dementia Associated with Parkinson's Disease Neurogenetics in Parkinson's Disease.- Impaired DNA Repair Systems Generate Mitochondrial Dysfunction and Increased Sensitivity.- Current Problems and Strategies in Motor Rehabilitation for Parkinson's Disease.- Critical Acute Akinesia in PD Patients Concomitant with Additional .Factors.a Lethal Combination.- Biomarkers for the Early Detection of Parkinson's Disease: An Essential Challenge.- Neurotransmitter and Neurotrophic Factor Secreting Cell Line Grafting For the Treatment of PD.- Novel Therapeutic Target in PD: Experimental Models.- Gene on PARK8 Locus in Families with Parkinsonism.- Microglia Activation and Gene Expression of Cytokines in Parkinson's Disease.- Dissecting the Biochemical Pathways Mediated by Genes Implicated in Parkinson's Disease.- Neuroinflammation in Early Stages of Alzheimer's and Parkinson's Disease.- Alzheimer's Disease, Parkinson's Diseases and Frontotemporal Dementias.- The Role of Oxidative Insult and Neuronal Survival in Alzheimer's and Parkinson's Diseases.- Redox Proteomics Identification of Oxidatively Modified Proteins in AD Brain and a Rodent Model of PD.- Biomarkers for Alzheimer's Disease and Parkinson's Disease.- Bioluminescent Imaging of Excitotoxic and Endotoxic Brain Injury in Living Mice.- The Alzheimer's Disease Neuroimaging Initiative.- Two Hits and You're Out? A Novel Mechanistic Hypothesis of Alzheimer's Disease.- Vascular Risk Factors and Risk for AD and MCI - Population Based Studies.- Cholesterol Transport and Production in Alzheimer's Disease Cholesterol and AB Production: Methods for the Analysis of Altered Cholesterol de Novo Synthesis.- Glycosaminoglycans and Analogs in Neurodegenerative Disorders.- Prospective Role of Glycosaminoglycans in Apoptosis Associated with Neurodegenerative Diseases.- Stem Cell Therapy in Alzheimer's Disease.- Oral AB Vaccine Using a Recombinant Adeno-associated Virus Vector is Safe and Efficient in AD Mouse.- In Vivo Targeting of Amyloid Plaques via Intranasal Administration of Phage Anti-B-Amyloid Antibodies Is Decreased Pro-DNF the Cause of Alzheimer-Associated Neurodegeneration and Cognitive Decline?.- Shift in the Balance of TRKA and Pro NGF in Prodromal Alzheimer's Disease Neuroprotective Effects of Trophic Factors.- Multiple Extracellular Kinases.- Intraneuronal AB and Alzheimer's Disease.- Physiological Processing of the Cellular Prion Protein and BAPP: Enzymes and Regulation.- Expression of Wnt Receptors, Frizzled, in Rat Neuronal Cells.- Cell Models of Tauopathy.- Co-expression of FTDP-17 Human Tau.Transgenic Mice.Tau Polymerization and Neurodegeneration.- Enhanced Activation of NF-kB Signalling by Apolipoprotein E4.- Pleiotropic Effects of APOE in Dementia.- Upregulation of the A-Secretase Pathway.- Frequency and Relationship of Argyrophilic Grain Disease and Thorn Shaped Astrocytes in AD.- Cellular Membranes as Targets in Amyloid Oligomer Disease.- Ganglioside-Dependent Generation of a Seed for Alzheimer Amyloid.- Evidence that the Amyloid Pathology Progresses in a Neurotransmitter Specific Manner.- Rationale for Glutamatergic and Cholinergic Approaches for the Treatment of Alzheimer's Disease.- Cortical Cholinergic Lesion Causes AB Deposition: A Cholinergic-Amyloid Fusion Hypothesis.- Expression of Acetylcholinesterase in Alzheimer's Disease Brain.- Role of B-Amyloid in the Pathophysiology of AD and Cholinesterase Inhibition.- Dissociation Between the Potent Amyloid-B Protein Pathway Inhibition and Cholinergic Actions of AChEIs etc.- Allosteric Potentiators of Neuronal Nicotinic Cholinergic Receptors.

Editorial Reviews

From the reviews:"This book is actually a compilation of chapters from selected invited speakers who attended the 7th International Congress on Alzheimer's and Parkinson's disease that took place in March 2005 in Italy. . The intended audience is . scientists studying Alzheimer and Parkinson disease."(Michael J. Schrift, Doody's Review Service, November, 2008)