Advances in Antiviral Drug Design

Other | July 1, 2007

byDe Clercq, E., E. De Clercq

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Regularly reviewing the "state-of-the-art" developments in the antiviral drug research field, this latest volume spans the conceptual design and chemical synthesis of new antiviral compounds. It discusses their structure-activity relationship, mechanism and targets of action, pharmacological behavior, antiviral activity spectrum, and therapeutic potential for clinical use.

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Regularly reviewing the "state-of-the-art" developments in the antiviral drug research field, this latest volume spans the conceptual design and chemical synthesis of new antiviral compounds. It discusses their structure-activity relationship, mechanism and targets of action, pharmacological behavior, antiviral activity spectrum, and t...

Format:OtherDimensions:264 pages, 1 × 1 × 1 inPublished:July 1, 2007Publisher:Elsevier ScienceLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0080548245

ISBN - 13:9780080548241

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Table of Contents

Status presens of antiviral drugs and strategies, Part I: DNA viruses and retroviruses
Status presens of antiviral drugs and strategies, Part II: RNA viruses (except retroviruses)
Methylenecyclopropane analogues of nucleosides as anti-herpes agents
Synthesis and antiviral evaluation of broad spectrum orally active analogs of cidofovir and other acyclic nucleoside phosphonates
CCR5 antagonists for the treatment of HIV infection and AIDS
The medicinal chemistry of the DATA and DAPY series of HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs)