Advances in Cancer Research

Other | December 1, 1994

byVande Woude, George F., George F. Vande Woude

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This volume contains reviews highlighting some of the most important achievements in understanding the molecular basis of cancer. Included are reviews on human papilloma virus and tumor suppressor gene products, the function of SH2 and SH3 domains in tyrosine kinase signal transduction, oncogene activation in mammary tumors, the phenotypes of polyoma middle T antigen in transgenic animals, and the role of protein kinase C and FCg receptors in neoplastic disease. Transgenic animal models for the study of molecular events in cancer are especially featured in these reviews.


* Highlights of Volume 64:
* Interactions of papilloma virus proteins with tumor suppressors
* Retinoblastoma tumor suppressor protein
* SH2 and SH3 domains in tyrosing kinase signal transduction
* Oncogene activation in mammary tumors
* Polyomavirus middle T antigen phenotypes in transgenic animals
* Protein kinase C and FCg receptors in neoplastic disease
* Transgenic mouse models for molecular carcinogenesis

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From the Publisher

This volume contains reviews highlighting some of the most important achievements in understanding the molecular basis of cancer. Included are reviews on human papilloma virus and tumor suppressor gene products, the function of SH2 and SH3 domains in tyrosine kinase signal transduction, oncogene activation in mammary tumors, the pheno...

Format:OtherDimensions:305 pages, 1 × 1 × 1 inPublished:December 1, 1994Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0080562469

ISBN - 13:9780080562469

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Table of Contents

Interactions between Papillomavirus Proteins and tumor Suppressor Gene Products,K.H. Vousden.
The Retinoblastoma Tumor Suppressor Protein,J.Y.J. Wange, E.S. Knudsen, and P.J. Welch.
SH2 and SH3 Domains in Signal Transduction,T. Pawson.
Activation of the Src Family of Tyrosine Kinases in Mammary Tumorigenesis,S.K. Muthuswamy and W.J. Muller.
Oncogenic Properties of the Middle T Antigens of Polyomaviruses,F. Kiefer, S.A. Courtneidge, and E.F. Wagner.
Selective Involvement of Protein Kinase C Isozymes in Differentiation and Neoplastic Transformation,J.Goodnight, H. Mischark, and J.F. Mushinski.
FC g Receptors in Malignancies: Friends of Enemies?J. Gergely and G. Sármay.
Dissecting Molecular Carcinogenesis: Development of Transgenic Mouse Models by Epidermal Gene Targeting,D.A. Greenhalgh and D.R. Roop.
Index.