Advances in Prostaglandin and Leukotriene Research: Basic Science and New Clinical Applications

byBengt SamuelssonEditorRodolfo Paoletti, Giancarlo Folco

Paperback | December 4, 2010

Advances in Prostaglandin and Leukotriene Research: Basic Science and New Clinical Applications by Bengt Samuelsson
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The 11th international Conference on ADVANCES IN PROSTAGLANDIN AND LEUKOTRIENE RESEARCH: BASICSCIENCEANDNEWCLlNICALApPLlCA TIONS was held, as in the past, in Florence, Italy, on June 4-8, 2000. A selection of lectures presented at the meeting is included in this volume, which continues the tradition of covering both basic and clinical aspects of prostaglandin and leukotriene research. At this meeting particular emphasis was given to the lipid mediator circuits of lipoxin and leukotrienes and to the expression ofthe COX2 gene. The plenary lectures by C.N. Serhan (Boston, Massachusetts, U.S.A.) and H.R. Herschman (Los Angeles, California, U.S.A.) were devoted to these areas, while S. Narumiya (Kyoto, Japan) and J.M. Drazen (Boston, Massachusetts, U.S.A.) presented the latest advances in the fields ofprostanoid receptors and the genetics of asthma. Specific sessions focused on vascular physiopathology, cell differentiation and cancer, and the cardiovascular system. Lipoxygenases were discussed in detail at the molecular and cellular levels and attention was given to signal transduction pathways for leukotrienes and prostanoids. K.F. Austen (Boston, Massachusetts, U.S.A.) and T. Izumi (Tokyo, Japan) clarified the role and regulation ofLTC synthase ofleukotriene biosynthesis. Other important sessions 4 described regulation and control of nitric oxide, cannabimimetic eicosanoids, and the roles of eicosanoids in neuroscience. Applied clinical sessions devoted to the respiratory system and inflammation, including cyclooxygenase pathways, concluded the meeting.
Preface. List of Contributors. I: Lipoxygenases and Leukotriene Biosynthesis. 1. Phosphorylation and Activation of 5-Lipoxygenase by P38 Kinase-Activated MAPKAP Kinases; O. Werz, et al. 2. 5-Lipoxygenase and the Nucleus: Where, When, How, and Why?; M. Peters-Golden, T.G. Brock. 3. Calcium Binding Site of 5-Lipoxygenase; T. Hammarberg, ...
Title:Advances in Prostaglandin and Leukotriene Research: Basic Science and New Clinical ApplicationsFormat:PaperbackProduct dimensions:206 pages, 24.4 X 17 X 0.01 inShipping dimensions:206 pages, 24.4 X 17 X 0.01 inPublished:December 4, 2010Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:9048158818

ISBN - 13:9789048158812

Appropriate for ages: All ages

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