Alzheimer's Disease: Advances in Genetics, Molecular and Cellular Biology

October 29, 2010|
Alzheimer's Disease: Advances in Genetics, Molecular and Cellular Biology by Sangram S. Sisodia
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This book examines every major aspect of Alzheimer disease at a time when there has been no scholarly research volume on the subject published in the last 3-5 years. This edition includes expanded coverage of the cellular-level exploration of related dementing disorders, with in-depth presentation of prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins.

The Genetics of Alzheimer's Disease.- APP Biology, Processing and Function.- The Biology of the Presenilin Complexes.- ?-secretase: Physiological Role and Target Validation.- Cognitive Impairment in Transgenic A? and Tau Models of Alzheimer's Disease.- Cholesterol and ?-Amyloid.- A? Structure and Aggregation.- Signaling Mechanisms that...
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Title:Alzheimer's Disease: Advances in Genetics, Molecular and Cellular Biology
Format:Paperback
Dimensions:286 pages, 23.5 X 15.5 X 0 in
Published:October 29, 2010
Publisher:Springer-Verlag/Sci-Tech/Trade
Language:English
Appropriate for ages:All ages
ISBN - 13:9781441941954

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