Alzheimers Disease and Its Variants: A Diagnostic and Therapeutic Guide

Paperback | June 11, 2010

byRichard J. Caselli, Pierre N. Tariot

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The number of patients with dementia is rising in proportion to the aging of our population; therefore, by 2050 the prevalence of Alzheimer's disease is expected to triple, risking the integrity of the entire U.S. healthcare economy. More NIH dollars are spent on Alzheimer's disease researchthan on any other neurological disease and our available fund of information has commensurately accelerated. Whereas 30 years ago little distinction was made between different forms of dementia, clinicians now distinguish multiple degenerative and vascular syndromes, each with their own etiologic,therapeutic and prognostic implications. New genetic insights reach the popular press on a regular basis. Consequently Alzheimer's disease (and related disorders) has become a special concern to the majority of the population whose main avenue of care lies with the primary care physician.The primary care physician (general internist, family practitioner, nurse practitioner), geriatrician, and geriatric psychiatrist are the target audiences for this book; in short anyone who is not a neurological expert who provides dementia-related care. As the primary care physician is the targetaudience for this title, the volume begins with a discusion of how to produce an effective diagnosis through a series of precise, easy- to- follow steps. Additional sections detail the current research state of each of the major individual dementia diseases that the general clinician frequentlyencounters. The last section procides a clinically focused 'how to' guide for treatment including symptom-directed pharmacotherapy, as well as an up-to-date summary of ongoing major therapeutic trials and an assessment non-pharmacological management issues such as driving and end-of- lifeconsiderations. Aiming to be clear, consice and practical, this volume provides the essential information in dementia related care, from disease diagnosis to symptom management. Because it uses the most up-to-date dementia research available, this volume will become a close companion of theprimary care physician, who seeks direct answers to the common questions and issues that arise in the diagnosis and management of patients with dementia.

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From the Publisher

The number of patients with dementia is rising in proportion to the aging of our population; therefore, by 2050 the prevalence of Alzheimer's disease is expected to triple, risking the integrity of the entire U.S. healthcare economy. More NIH dollars are spent on Alzheimer's disease researchthan on any other neurological disease and o...

Richard J. Caselli, M.D. is Professor and Chair, Department of Neurology, Mayo Clinic in Arizona and member of the Mayo Clinic Arizona Executive Board. He is also Clinical Core Director of the Arizona Alzheimer's Disease Center which comprises the six major academic tertiary care medical centers in Maricopa and Pima Counties. He is ...
Format:PaperbackDimensions:264 pages, 5 × 7.91 × 0.71 inPublished:June 11, 2010Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0195393384

ISBN - 13:9780195393385

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Table of Contents

Section A: The Diagnosis and Evaluation of Dementia1. Normal Aging and Memory Decline2. Characterizing a Cognitive Disorder3. Diagnostic Evaluation of Suspected Alzheimer's Disease4. When It's Not Alzheimer's Disease: Four Brief Illustrative Cases of Reversible "Dementias"Section B: Alzheimer's Disease and Its Clinical Syndromes5. The Neurobiology of Alzheimer's Disease6. The Classic Clinical Syndromes of Alzheimer's Disease7. Clinical Variants of Alzheimer's Disease8. Neuropathological Overlap SyndromesSection C: Pharmacotherapy of Alzheimer's Disease (And Other Forms of Demenetia): A Practical Approach to Medical Management9. Pharmacotherapy: Cognitive Impairment10. Pharmacotherapy: Behavioral Problems11. Pharmacotherapy: Other IssuesSection D: Nonpharmacological Management12. Acute Interventions13. Communicating With Dementia Patients14. Managing Problem Behaviors, Aggression, and Violence15. Planning Ahead: Legal Issues and Advance Directives16. The Long Term Care Continuum17. End of Life Care for Dementia18. Caring For the CaregiverSection E. Experimental and Future Therapies19. Neurotransmitter-Based Interventions20. Amyloid-Based Interventions21. Tau-Based Interventions22. Other Agents