Amino Acid and Peptide Synthesis

Paperback | August 15, 2002

byJohn Jones

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The study of amino acids and peptides is becoming increasingly important to chemists becuase of the growing overlap of mainstream organic chemistry with bioorganic chemistry and biochemistry. This introductory text begins with a brief survey of the role and diversity of amino acids, peptides,and proteins in nature, and goes on to describe and explain the principal methods of chemical synthesis. With its emphasis on chemical principles and strategies rather than detailed technical matters, the book will be essential reading for all students of chemistry and biochemistry with an interestin this important field. This second edition contains extensive additions and adjustments, to present a completely up-to-date account of the chemical essentials of mainstream peptide synthesis.

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The study of amino acids and peptides is becoming increasingly important to chemists becuase of the growing overlap of mainstream organic chemistry with bioorganic chemistry and biochemistry. This introductory text begins with a brief survey of the role and diversity of amino acids, peptides,and proteins in nature, and goes on to descr...

John Jones was active in mainstream peptide chemistry for over 30 years and and made a number of important contributions, especially the development of a novel histidine side chain protecting group. His interests have recently been drawn away from conventional peptide chemistry into peptidomimetics based on carbohydrate-derived buildi...

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Format:PaperbackDimensions:96 pages, 9.69 × 7.44 × 0.22 inPublished:August 15, 2002Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199257388

ISBN - 13:9780199257386

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Table of Contents

1. Introduction2. a-Amino acid synthesis3. a-Amino protection4. a-Carboxy protection5. Peptide bond formation6. Residue-specific considerations7. Strategy and tactics8. Solution peptide synthesis9. Solid phase peptide synthesis10. GFP, a tour de forceAppendix A Abbreviations and their useAppendix B Further reading and general sourcesIndex

Editorial Reviews

`The subject is presented authoritatively, concisely and lucidly.'Sue Brown, Aslib Book Guide