Amyotrophic Lateral Sclerosis and the Frontotemporal Dementias

Hardcover | November 1, 2012

EditorMichael J. Strong

not yet rated|write a review
Over the past ten years, there has been an increasing recognition that syndromes of frontotemporal dysfunction (FTD) are a common occurrence in patients with amyotrophic lateral sclerosis (ALS). Such syndromes may be present in as many as 60% of patients with ALS. Conversely, the occurrence ofmotor neuron dysfunction in patients with clinically pure frontotemporal dementia is increasingly recognized. This suggests that to some extent there are overlapping syndromes in which both ALS and FTD occur within the same individual. This volume summarizes the advances in our understanding of these two disorders, as well as the potential relationship between the two. Key topics include advances in our ability to clinically describe the frontotemporal syndromes, preclinical detection, neuroimaging, and genetics. The explodingfield of new markers in neuropathology is examined, as is the role of new genetic mutations in DNA/RNA transport systems. This book is the essential reference text for this topic, and will be of interest to neurologists and neurological trainees with a clinical or research interest in the FTDs orALS, neuropsychologists, neuropathologists, and researchers.

Pricing and Purchase Info

$107.68 online
$162.95 list price (save 33%)
Ships within 1-3 weeks
Ships free on orders over $25

From the Publisher

Over the past ten years, there has been an increasing recognition that syndromes of frontotemporal dysfunction (FTD) are a common occurrence in patients with amyotrophic lateral sclerosis (ALS). Such syndromes may be present in as many as 60% of patients with ALS. Conversely, the occurrence ofmotor neuron dysfunction in patients with c...

Dr. Michael Strong is Dean of the Schulich School of Medicine and Dentistry at the University of Western Ontario, a Distinguished University Professor and the Arthur J. Hudson Chair in ALS Research. Dr Strong is a scientist at the Robarts Research Institute, and has also served as co-chair of the Canadian ALS Research Consortium and is...

other books by Michael J. Strong

ADHD voor dummies
ADHD voor dummies

Kobo ebook|Sep 13 2013

$13.59 online$17.54list price(save 22%)
see all books by Michael J. Strong
Format:HardcoverDimensions:438 pages, 9.69 × 6.73 × 0.98 inPublished:November 1, 2012Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199590672

ISBN - 13:9780199590674

Look for similar items by category:

Customer Reviews of Amyotrophic Lateral Sclerosis and the Frontotemporal Dementias

Reviews

Extra Content

Table of Contents

1. Ralph M. Garruto: Lessons from the study of natural experiments of hyperendemic foci of neurodegeneration2. Jeffrey Rosenfeld: The motor neuron diseases3. Shigeki Kuzuhara and Yasumasa Kokubo: Amyotrophic lateral sclerosis-Pakinsonism-Dementia complex in the Kii peninsula of Japan (Muro disease): a review on recent research and new concept4. Alexandre Henri-Bhargava and Morris Freedman: The frontotemporal dementias: an overview5. J. B. Orange and A. E. Hillis: Language profiles in amyotrophic lateral sclerosis6. Hiroo Ichikawa, Sotaro Hieda, Hideki Ohno, Kenji Ishihara, and Mitsuru Kawamura: Language impairment in amyotrophic lateral sclerosis from an historical review: kana and kanji versus alphabetical languages7. Mitsuru Kawamura and Hiroo Ichikawa: Amyotrophic lateral sclerosis with dementia: neuropsychological aspects8. Sharon Abrahams and Christopher Kipps: Social cognition in frontotemporal dementia and amyotrophic lateral sclerosis9. Laura H. Goldstein: Behavioural change in amyotrophic lateral sclerosis10. Jennifer Murphy, Fizaa Ahmed, and Catherine Lomen-Hoerth: Cognition in amyotrophic lateral sclerosis11. Vincenzo Silani, Barbara Poletti, and Stefano Zago: Frontotemporal syndromes of primary lateral sclerosis12. Jeremy M. Shefner: Electrophysiological evaluation of lower motor neuron loss in amyotrophic lateral sclerosis13. Jan Kassubek and Albert C. Ludolph: Multimodality approach to neuroimaging in amyotrophic lateral sclerosis/frontotemporal dementia14. Sandra E. Black and Yana Yunusova: Using neuroimaging to understand brain-behaviour relationships in the context of motor neuron disease15. S. Kalra: Amyotrophic lateral sclerosis and the frontotemporal dementias: using neuroimaging to quantitate disease progression16. Tiffany W. Chow: Differentiating normal from pathological atrophy: when is frontotemporal atrophy normal?17. Robert Bowser, James Connor, and Martin Turner: Cerebrospinal fluid-based biomarkers for amyotrophic lateral sclerosis18. Nigel J. Cairns: Neuropathology of frontotemporal lobar degeneration19. J. Robin Highley and Paul G. Ince: The neuropathology of the motor neurone diseases20. Bryan J. Traynor and Stuart Pickering-Brown: Genetics of frontotemporal dementia21. Ashley Jones and Ammar Al-Chalabi: Genetics of the MNDs22. Kathryn Volkening and Michael J. Strong: Perturbed RNA metabolism in amyotrophic lateral sclerosis23. Michael J. Strong, Wencheng Yang, May Gohar, and Wendy L. Strong: Alterations in tau metabolism in amyotrophic lateral sclerosis with cognitive impairment24. Emanuele Buratti: Transactive response DNA-binding protein of 43 kDa25. Jennifer Gass and Leonard Petrucelli: Progranulin