An Insiders Guide to Clinical Trials

Paperback | May 13, 2011

byCurtis L. Meinert

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Clinical trials receive a lot of media attention; we hear or read about them almost daily in reports heralding new and promising treatments or reports raising questions about the safety or efficacy of an established treatment. The randomized trial is the foundation of evidence-based medicineand the cornerstone for comparative effectiveness research.This book is designed for budding students of clinical trials, novice researchers, and for the serious lay reader wanting to know more about the inner workings of trials, how they are reported, who and what gets studied, what to make of results, and how to shop for trials as a patient. Written withwit and charm, this guide will interest readers in a way that formal, didactic texts cannot.

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Clinical trials receive a lot of media attention; we hear or read about them almost daily in reports heralding new and promising treatments or reports raising questions about the safety or efficacy of an established treatment. The randomized trial is the foundation of evidence-based medicineand the cornerstone for comparative effective...

Curtis L. Meinert, PhD, is a Professor in the Departments of Epidemiology and Biostatistics at the Johns Hopkins Bloomberg School of Public Health. He was founder of the Center for Clinical Trials and served as its director through September 2005. He was a founding member of the Society for Clinical Trials and was Editor of Control...

other books by Curtis L. Meinert

ClinicalTrials: Design, Conduct and Analysis
ClinicalTrials: Design, Conduct and Analysis

Hardcover|Mar 1 2012

$116.07 online$125.00list price(save 7%)
Format:PaperbackDimensions:320 pages, 8.25 × 5.5 × 0.68 inPublished:May 13, 2011Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199742960

ISBN - 13:9780199742967

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Table of Contents

Preface1. Introduction2. The language of clinical trials3. The recipe for trials4. The stages of trials5. The anatomy of trials6. Authorship and credits7. The nature of trials8. The ethics of trials9. Regulation of trials10. Research misconduct11. Myths regarding trials12. "Tricks" of the trade from a cynic13. Reading between the lines, or how to read a journal article14. Critics and criticisms15. What to make of results16. Biostatistics 10117. Subgroup analysis vs data dredging18. Meta-analysis and systematic reviews19. Re-Search20. Shopping for a trial?21. Readings22. Clinical trials and our health23. Final exam24. Last wordsAppendix:The Mother Test for Designers of TrialsRating Index for Clinical TrialsA Patient's Guide for Deciding Whether to Enroll in a Randomized TrialAbbreviationsReferencesIndex