Angelo Mossos Circulation of Blood in the Human Brain

Hardcover | October 8, 2014

byMarcus E. Raichle, Gordon M. Shepherd

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Modern brain imaging is revolutionizing the study of brain function in health and disease. Few realize that its origins began with a pioneering study in the nineteenth century by an Italian scientist, Angelo Mosso, of several subjects brought to him with head injuries that exposed their brainsto direct observation. He took advantage of this opportunity to observe for the first time changes in cerebral blood flow in relation to different behaviors, the same changes that are the basis for the measurements underlying modern methods.Although Mosso was widely recognized for this highly original study by his contemporaries, through a German translation in 1881, there has never been a translation through which his magnificent achievement could be recognized in English. His rightful role as the pioneer in brain imaging has thus notbeen recognized. This unique volume corrects that deficiency. Through it, the modern reader, whether an expert in the field or an interested scientist or member of the public, can gain a new perspective on the remarkable insights Mosso gained into how behaviors as subtle as thinking about a subjector feeling an emotion can produce the changes in pulsations of the brain that he observed. The special features of this volume begin with a brief summary of Mosso's life. Two pioneers of modern brain imaging, Marcus Raichle and Gordon M. Shepherd, then provide an extensive commentary that succinctly summarizes Mosso's work and explains its relevance to modern methods. The authors not onlyemphasize Mosso's role as a pioneer in brain imaging, but also through this study as a pioneer in the eventual rise of cognitive neuroscience. The English translation then follows, together with all of the plates and illustrations of the original volume. The result is a classic of neuroscience nowavailable for wide appreciation by neuroscientists, neurologists, psychologists, psychiatrists, historians of science and medicine, and the general public.

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Modern brain imaging is revolutionizing the study of brain function in health and disease. Few realize that its origins began with a pioneering study in the nineteenth century by an Italian scientist, Angelo Mosso, of several subjects brought to him with head injuries that exposed their brainsto direct observation. He took advantage of...

Marcus E. Raichle, MD, PhD, is Professor in the departments of Radiology, Neurology, Anatomy and Neurobiology at Washington University School of Medicine. Gordon M. Shepherd is Profess of Neurobiology in the Department of Neurobiology at Yale University Medical School.
Format:HardcoverDimensions:208 pages, 9.25 × 6.12 × 0.98 inPublished:October 8, 2014Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199358982

ISBN - 13:9780199358984

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Table of Contents

IntroductionBrief Biography of Angelo Mosso and His TimesCommentary: From Mosso to Modern Brain ImagingNote on the TranslationCritical Historical IntroductionTranslation: The Circulation of the Blood in the Human Brain1. Notes concerning the disease states of the three subjects in whom the conditions of the cerebral circulation were studied2. Description of the apparatus used to record the pulse of the brain and of other parts of the body3. General information concerning the form of the puls4. Concerning the response of the cerebral circulation during enhanced mental activity and during emotional and sensory impressionsSleep and its relationship to the cerebral circulation:1. Observations on Catherina X2. Observations on Thron during sleep3. Observations on Caudana during sleep4. Observations on Bertino during sleep5. Chloral hydrate induced sleep6. Considerations about the nature of sleep and its concomitant manifestations7. Concerning the variations of the cerebral tracings, which depended on the motions of the vessels and of the heart8. Concerning the movements of the blood vessels in the external ear of the rabbit L9. The influence of breathing on the circulation of the blood in the brain and in the lungs10. Experimental critique of the investigations on the pulmonary circulation undertaken11. The influence of breathing on the systemic (general) circulation12. The influence of amyl nitrite on the blood circulation in the brain13. Anemia and hyperemia of the brain14. Concerning the circulation of the blood within the intact skull15. Investigations concerning the movements of the cerebrospinal fluid