Animal Cells as Bioreactors by Terence CartwrightAnimal Cells as Bioreactors by Terence Cartwright

Animal Cells as Bioreactors

byTerence Cartwright

Paperback | March 19, 2009

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This book covers all aspects of the new technologies needed to turn animal cells into an acceptable and cost-effective tool for drug production. This includes modifying them genetically so that they produce the right product in high yield, getting them to grow reproducibly on an industrial scale, and extracting the required product from them. It also covers biological safety issues, and the verification of the chemical and biological nature of the protein drug produced. The work covers the latest developments in all of these areas and how they all need to be integrated for the design of an effective biotechnological production process.
Title:Animal Cells as BioreactorsFormat:PaperbackDimensions:196 pages, 9.02 × 5.98 × 0.43 inPublished:March 19, 2009Publisher:Cambridge University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:052110310X

ISBN - 13:9780521103107


Table of Contents

1. Introducing the animal cell as a bioreactor; 2. Yield of recombinant product: engineering cells for maximum expression; 3. The generation of biomass, medium design for animal cell culture, fermenter design for animal cell culture, suspension cultures, immobilized cells, process control; 4. Adjusting cellular metabolism for optimum product yield; 5. Downstream processing; 6. Regulatory aspects of using cells as bioreactors, viral contamination of animal cell derived pharmaceuticals; 7. Overview and conclusions; References; Index.

Editorial Reviews

"The book is easy to follow and it serves as a good introduction to the biologists who wishes to start using animal cell biotechnology. Animal Cells as Bioreactor is a well written and documented text. The book contains much information and so will be useful equally as a textbook and a reference book to students, teachers and scientists who are active in biotechnology research and development." Canadian Society of Microbiologists Newsletter