Antenatal and Neonatal Screening

Hardcover | November 1, 2000

EditorNicholas Wald, Ian Leck

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The options in antenatal and neonatal care are legion. Preferences still tend to be subjective. In spite of much publicity that has raised public expectation, an up-to-date thorough evaluation of antenatal and neonatal screening was lacking. This book sets out screening approaches in aquantitative manner and will enable choices to be based on objective evidence of efficacy and, where appropriate, safety. Technical advances have sometimes been introduced uncritically and without adequate assessment. It has been assumed, perhaps naively, that the early detection of abnormality willinvariably be a good thing. In this book, there is no such assumption that new tests or technical procedures are useful. They are only considered as a legitimate medical option if they can and have been shown to lead to improvements in outcome. Each disorder is defined and the screening procedurewhich is designed to identify the disorder critically evaluated. Priority is given to the screening of disorders which lend themselves to effective intervention and practical guidance is provided on how screening should be conducted. Most chapters include a discussion of problem areas and researchneeds. There are 23 chapters from leading experts from Europe and North America. The book bridges different disciplines concerned with screening and thereby improves the understanding of the subject and will improve delivery of preventive medical services. The book is directed at obstetricians,public health doctors, paediatricians and fetal medicine doctors, epidemiologists, geneticists, health care providers and administrators.

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From the Publisher

The options in antenatal and neonatal care are legion. Preferences still tend to be subjective. In spite of much publicity that has raised public expectation, an up-to-date thorough evaluation of antenatal and neonatal screening was lacking. This book sets out screening approaches in aquantitative manner and will enable choices to be b...

Nicholas Wald is at Wolfson Institute, University of London. Ian Leck is at University of Manchester.
Format:HardcoverPublished:November 1, 2000Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0192628267

ISBN - 13:9780192628268

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Table of Contents

Foreword Richard DollIntroductionPrinciples of screening I: single testsPrinciples of screening II: multiple testsPart I: Screening for Specific DisordersDisorders principally affecting the fetus or neonateNeural Tube defectsDown's syndromeX-linked disordersTay-Sachs diseaseGenetic haematological disordersCystic fibrosisPhenylketonuria and other inherited metabolic defectsCongenital hypothyroidismCongenital dislocation of the hipDisorders affecting the mother and the fetus or neonateAcquired haematological disordersFetal and neonatal haemolytic diseaseInfections in the fetus and newborn infantMaternal and fetal disorders associated with high blood pressurePart II: Certain Procedures used in ScreeningUltrasound as an ancillary investigation in the management of pregnancyUltrasound scanning for congenital abnormalitiesAmniocentesis and chorionic villus samplingFetal blood and tissue samplingContinuous electronic fetal monitoring during labourPart III: Wider IssuesThe ethics of antenatal and neonatal screeningConclusions

Editorial Reviews

`This textbook is recommended for both policy makers and health care professionals working in the fields of maternal and child health care.'International Journal of Epidemiology