Antifungal Agents by Erika J. ErnstAntifungal Agents by Erika J. Ernst

Antifungal Agents

EditorErika J. Ernst

Paperback | November 10, 2010

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A collection of state-of-the-art molecular methods for studying antifungal resistance, for discovering and evaluating both new and existing antifungal drugs, and for understanding the host response and immunotherapy of such agents. The protocols follow the successful Methods in Molecular MedicineT series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Antifungal Agents: Methods and Protocols offers clinician-scientists, microbiologists and molecular biologists the productive tools they need today to understand and successfully develop new therapeutic agents for yeast, mold, and fungal infections.
Title:Antifungal AgentsFormat:PaperbackDimensions:220 pages, 9.02 × 5.98 × 0 inPublished:November 10, 2010Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617374679

ISBN - 13:9781617374678

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Table of Contents

Part I. IntroductionSusceptibility Testing Methods of Antifungal AgentsErika J. ErnstPart II. Antifungal ResistanceDeoxyribonucleic Acid Fingerprinting Methods for Candida SpeciesShawn R. Lockhart, Claude Pujol, Andrew R. Dodgson, and David R. SollCARE-2 Fingerprinting of Candida albicans IsolatesJoachim Morschhäuser, Peter Staib, and Gerwald KöhlerTargeted Gene Deletion in Candida albicans Wild-Type Strains by MPAR FlippingJoachim Morschhäuser, Peter Staib, and Gerwald KöhlerApplication of Deoxyribonucleic Acid Microarray Analysis to the Study of Azole Antifungal Resistance in Candida albicansKatherine S. Barker and P. David RogersApplication of Proteomic Analysis to the Study of Azole Antifungal Resistance in Candida albicansMassoumeh Z. Hooshdaran, George M. Hilliard, and P. David RogersTechniques for Antifungal Susceptibility Testing of Candida albicans BiofilmsGordon Ramage and José Luis López-RibotPart III. Antifungal Development and EvaluationNatural Products and Antifungal Drug DiscoveryMelissa R. Jacob and Larry A. WalkerUse of an Animal Model of Disseminated Candidiasis in the Evaluation of Antifungal TherapyDavid AndesMurine Model of Invasive AspergillosisRussell E. Lewis and Nathan P. WiederholdAntifungal CombinationsRoxana G. Vitale, Javier Afeltra, and Eric DannaouiPost-Antifungal Effect MethodsRoxana G. VitalePart IV. Host Responses and ImmunotherapyEvaluation of Immunotherapy in Invasive Candidiasis: Antifungal Activity and Cytokine Expression AssaysMaria Simitsopoulou and Emmanuel RoilidesInteraction of Histoplasma capsulatum With Human Macrophages, Dendritic Cells, and NeutrophilsSimon L. NewmanImmunology of Infection Caused by Cryptococcus neoformansFloyd L. Wormley, Jr. and John R. PerfectIndex

Editorial Reviews

From the reviews:"Due to the increased prevalence in systemic fungal infections worldwide, more knowledge is needed about antifungal drug testing and research is very important. This book, which is one in the series of 'Methods in Molecular Medicine', describes both traditional and new techniques for the investigation of antifungal resistance and for the development and evaluation of new compounds. . By and large, this is an interesting book for mycological researchers in both laboratory and clinical medicine." (Prof. Jan Faergemann, Acta Dermato-Venereologica, Vol. 86, August, 2006)