Antiviral Strategies by Hans-Georg KräusslichAntiviral Strategies by Hans-Georg Kräusslich

Antiviral Strategies

EditorHans-Georg Kräusslich, Ralf Bartenschlager

Hardcover | December 3, 2008

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A crucial issue for antiviral therapy is the fact that all antiviral substances rapidly select for resistance; thus, monitoring and overcoming resistance has become a most important clinical paradigm of antiviral therapy. This calls for cautious use of antiviral drugs and implementation of combination therapies. In parallel, efforts in drug discovery have to be continued to develop compounds with novel mode-of-action and activity against resistant strains. This book reviews the current status of antiviral therapy, from the roads to development of new compounds to their clinical use and cost effectiveness. Individual chapters address in more detail all available drug classes and outline new approaches currently under development.
Title:Antiviral StrategiesFormat:HardcoverDimensions:390 pagesPublished:December 3, 2008Publisher:Springer Berlin HeidelbergLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3540790853

ISBN - 13:9783540790853

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Table of Contents

Antiviral Strategies. Approaches for the Development of Antiviral Compounds: The Case of Hepatitis C Virus. Chain Terminators as Polymerase Inhibitors. Viral Protease Inhibitors. Anti-influenza Drugs: The Development of Sialidase Inhibitors. Other Inhibitors of Viral Enzymes and Function. Inhibitors of Viral Entry Immunomodulation Therapy. Nucleic Acids Based Therapeutics in the Battle Against Pathogenic Viruses.

Editorial Reviews

Aus den Rezensionen:"Dieses umfassende Werk gibt einen aktuellen und detaillierten Überblick über diverse virale Erreger und deren Therapiemöglichkeiten. Vorgestellt werden die ... Medikamentenklassen und in Entwicklung befindliche Behandlungsansätze." (in: Neurologie Psychiatrie, 2008, Issue 5, S. 51)