Apoptosis: A Practical Approach

Paperback | December 9, 1999

EditorGeorge Studzinski

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This text is designed to provide conceptual outlines and detailed procedures for basic and advanced studies of cell death by apoptosis. Chapters on the recognition of apoptosis as distinguished from necrosis and nonspecific cell DNA damage, are followed by a systematic examination of theestablished and the principal novel methodologies utilized by some leading laboratories conducting research on apoptosis. The organization is on the lines of signalling for apoptosis, the apoptotic cascade, and the execution of apoptosis. A wide variety of procedures are provided which will enablethe reader to participate in cutting-edge research.

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This text is designed to provide conceptual outlines and detailed procedures for basic and advanced studies of cell death by apoptosis. Chapters on the recognition of apoptosis as distinguished from necrosis and nonspecific cell DNA damage, are followed by a systematic examination of theestablished and the principal novel methodologi...

George Studzinski is at New Jersey Medical School.
Format:PaperbackPublished:December 9, 1999Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199637857

ISBN - 13:9780199637850

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Table of Contents

Preface1. Studzinski: Overview of Apoptosis2. Wilson and Potten: The Morphological Recognition of Apoptosis3. Yoshida, Shao and Pommier: Assessment of DNA Damage in Apoptosis4. Darzynkiewicz, Bedner and Li: Analysis of Cell Death by Flow and Laser Scanning Cytometry5. Naval and Anel: Cell-mediated Cytotoxicity and Cell Death Receptors6. Jenkins and Hannun: Sphingolipids as Messengers of Cell Death7. Van Engeland et al: Cytochemical Detection of Cyto- and Nucleoskeletal Changes During Apoptosis8. Costa-Pereira and Cotter: 9. Reed et al: Methods of Measuring Bcl-2 Family Proteins and Their Functions10. Blajeski and Kaufmann: Methods for Detecting Proteolysis During Apoptosis in Intact CellsIndex

Editorial Reviews

"The major strength of this book is the wealth of apaptosis-associated protocols provided by the authors ... a significant addition to the apaptosis literature and particularly valuable for mammalian cell biologists" Trends in Cell Biology