Application of Apoptosis to Cancer Treatment by Mels SluyserApplication of Apoptosis to Cancer Treatment by Mels Sluyser

Application of Apoptosis to Cancer Treatment

byMels Sluyser

Paperback | October 19, 2010

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Novel drugs are being developed which interact with the programmed cell death (apoptotic) machinery in cancer cells, thereby causing these cells to commit suicide and to be removed from the body. Research is also directed to investigate why the cancer cells sometimes lose the ability to undergo apoptosis after a certain period of time and methods are being developed to reactivate this cell death process. This book is intended for workers in the field and clinicians as a useful guide of the state of affairs in this exciting field which may offer more effective possibilities for treatment of cancer patients. Mels Sluyser is the Editor of the journals APOPTOSIS and ANTI-CANCER DRUGS. He brings together a collection of papers written by the world's leading experts in these fields.
Title:Application of Apoptosis to Cancer TreatmentFormat:PaperbackDimensions:377 pagesPublished:October 19, 2010Publisher:Springer NetherlandsLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:9048168333

ISBN - 13:9789048168330

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Table of Contents

Chapter 1: Disfunction of the Apoptotic Pathway in Cancer Cells by Lily YangChapter 2: Calcium Signaling and Apoptosis Resistance of Cancer Cells by Natalia Prevarskaya, Roman Skryma and Yaroslav ShubaChapter 3: Cell Clearance and Cancer by Bengt FadeelChapter 4: Specific, Pro-Poptotic Cell-Signaling: Design of Novel, Recombinant Targeted Antitumor Agents Operating Exclusively Through Modulation of Cellular Apoptotic Events: Novel, Targeted Pro-Apoptotic Therapeutic Agents by Yuying Liu, Lawrence H. Cheung and Michael G. RosenblumChapter 5: Targeting Oncogenes which Regulate Apoptosis by Andrew C. PhillipsChapter 6: Targeting Cyclins to Cause Cancer Cell Apoptosis by Suparna Mazumder, Dragos Plesca and Alexandru AlmasanChapter 7: Apoptosis Induction by Tumor-Targeted Toxins by Andrew ThorburnChapter 8: Targeting Cell-Death Pathways in Multiple Myeloma: Therapeutic Implications by Dharminder Chauhan and Kenneth AndersonChapter 9: Cephalostatin 1-Induced Apoptosis in Tumor Cells Selective Induction of Smac/DIABLO Release by Verena M. Dirsch and Angelika M. VollmarChapter10: Hamlet; a Novel Tool to Identify Apoptotic Pathways in Tumor Cells 223 by Caroline Düringer, Oskar Hallgren, Lotta Gustafsson, Jenny Petterson, Ann-Kristin Mossberg, Taras Manilov and Catharina SvanborgChapter 11: Cancer Immunotherapy: On the Trail of a Cure? by Thomas S. Griffith, Troy J. Kemp1, Aaron T. Ludwig, Jill M. Moore, and Rebecca L. VanOostenChapter 12: Histone Deacetylase Inhibitors as a Treatment of Trail-Resistant Cancers by Jiri Neuzil, Ladislav Andera and Brian GabrielliChapter 13: Basis of Cell Kill Following Clinical Radiotherapy by Oliver Faulhaber and Robert G BristowChapter 14: Imaging of Apoptotic Cells in Vivo by Juhana HakumäkiChapter15: Apoptosis-Inducing Anticancer Drugs in Clinical Trials by Wei Hu and John J. Kavanagh