Arterial Chemoreceptors: Arterial Chemoreceptors by Constancio GonzalezArterial Chemoreceptors: Arterial Chemoreceptors by Constancio Gonzalez

Arterial Chemoreceptors: Arterial Chemoreceptors

EditorConstancio Gonzalez, Colin A. Nurse, Chris Peers

Paperback | October 22, 2010

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The carotid body arterial chemoreceptors constitute unique sensory receptors capable of rapidly monitoring the levels of arterial blood oxygen and carbon dioxide. Whenever necessary they initiate homeostatic reflexes aimed to correct the detected deviations. Chemoreceptor cells of the carotid body constitute ideal models to study the entire processes of O2-sensing as well as CO2-sensing.The present book represents an updated review of the physiology of the carotid body chemoreceptors. Most important, the book provides the trends in the field as it contains results in the topics that are at the frontiers of future developments in O2-sensing in chemoreceptor cells. Additionally, it contains data from studies carried in other O2-sensing tissues including pulmonary vasculature and erythropoietin producing cells as well as on central CO2/pH chemoreceptors.Arterial Chemoreceptors should be considered as a prime source of information and as a guideline to every researcher in the field of arterial chemoreception in the years to come. It is also an important source of information for researchers and clinicians in the fields of hypoxic pulmonary vasoconstriction and pulmonary hypertension as well as for researchers in the field of erythropoietin and central chemoreceptors.
Title:Arterial Chemoreceptors: Arterial ChemoreceptorsFormat:PaperbackDimensions:488 pages, 9.25 × 6.1 × 0.07 inPublished:October 22, 2010Publisher:Springer NetherlandsLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:9048184835

ISBN - 13:9789048184835

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Table of Contents

The Discovery of Sensory Nature of the Carotid Bodies. Invited Article; F. De Castro. Fifty Years of Progress in Carotid Body Physiology. Invited article; R. S. Fitzgerald, C. Eyzaguirre and P. Zapata. Carotid Body: New Stimuli and New Preparations. Invited article; Colin A. Nurse. Enzyme-Linked Acute Oxygen Sensing In Airway And Arterial Chemoreceptors. Invited article; Paul J Kemp & C Peers. Cysteine Residues in the C-terminal tail of the Human BKCaa Subunit are Important for Channel Sensitivity to Carbon Monoxide; S.P. Brazier, V. Telezkhin, R. Mears, C.T. Müller, D. Riccardi and P.J. Kemp. Modulation of O2 Sensitive K+ Channels by AMP-activated Protein Kinase; M.L Dallas, J.L Scragg, C.N. Wyatt, F. Ross, D.G Hardie, A.M Evans and C Peers. Hydrogen Sulfide Inhibits Human BKCa Channels; V. Telezhkin, S. P. Brazier, S. Cayzac, C. T. Müller, D. Riccardi and D P. J. Kemp. DPPX Modifies TEA Sensitivity of the Kv4 Channels in Rabbit Carotid Body Chemoreceptor Cells; O. Colinas, F.D. Pérez-Carretero, E. Alonso, J.R. López-López and M. T. Pérez-García. Sustained Hypoxia Enhances TASK-like Current Inhibition by Acute Hypoxia in Rat Carotid Body Type-I Cells; F. Ortiz, R. Iturriaga and R. Varas. Inhibition of L-type Ca2+ Channels by Carbon Monoxide; M.L. Dallas, J.L. Scragg and C. Peers. Effects of the Polyamine Spermine on Arterial Chemo-Reception; S. Cayzac, A. Rocher, A. Obeso, C. González, P.J. Kemp and D. Riccardi. RT-PCR and Pharmacological Analysis of L-and T-Type Calcium Channels in Rat Carotid Body; A.I. Cáceres, E. González-Obeso, C. González and A. Rocher. Functional characterization of phosphodiesterases 4 in the rat carotid body: effect of oxygen concentrations; A.R. Nunes, J.R. Batuca and E.C. Monteiro. Calcium sensitivity for hypoxia in PGNs with PC-12 cells in co-culture; Patel GP, Baby SM, Roy A, Lahiri S. Modification of relative gene expression ratio obtained from real time qPCR with whole carotid body by using mathematical equations; J.H. Kim, I. Kim, and J.L. Carroll. Neurotransmitters in Carotid Body Function: The Case of Dopamine. Invited article; R. Iturriaga, J. Alcayaga, and C. González. Adenosine in peripheral chemoreception: new insights into a historically overlooked molecule. Invited article; S. V. Conde, E.C. Monteiro, A. Obeso and C. Gonzalez. The A2B-D2 receptor interaction that controls carotid body catecholamines release locates between the last two steps of hypoxic transduction cascade; S. V. Conde, A. Obeso, Monteiro EC. and C. Gonzalez. Benzodiazepines and GABA-GABAA Receptor System in the Cat Carotid Body; A. Igarashi, N. Zadzilka, M. Shirahata. Evidence For Histamine As a New Modulator of Carotid Body Chemoreception; R. Del Rio, E.A. Moya, J. Alcayaga and R. Iturriaga. Fluoresceinated Peanut Agglutinin (PNA) is a Marker for Live O2 Sensing Glomus Cells in Rat Carotid Body; I. Kim, D.J. Yang, D.F. Donnelly and J.L. Carroll. Neuroglobin in Aging Carotid Bodies; V. Verratti, C. Di Giulio, G. Bianchi, M. Cacchio, G. Petruccelli, C. Di Giulio, L. Artese, S. LahiriI and R. Iturriaga. Oxygen sensing and the activation of the Hypoxia Inducible Factor 1 (HIF-1). Invited article; Joachim Fandrey1 & Max Gassmann2 .Upregulation of Erythropoietin and its Receptor Expression in the Rat Carotid Body during Chronic and Intermittent Hypoxia; S.Y. Lam, G.L. Tipoe, and M.L. Fung. Iron Chelation and the Ventilatory Response to Hypoxia; Mieczyslaw Pokorski, Justyna Antosiewicz, Camillo, Di Giulio, and Sukhamay Lahiri. Systemic Effects Resulting From Carotid Body Stimulation Invited article; Prem Kumar. Bicarbonate-Regulated Soluble Adenylyl Cyclase (sAC) mRNA Expression and Activity in Peripheral Chemoreceptors; A. R. Nunes, E. C. Monteiro, S. M. Jonhson,E. B. Gauda. Developmental Maturation of Chemosensitivity to Hypoxia of Peripheral Arterial Chemoreceptors. Invited article; Estelle B. Gauda, John L. Carroll, David F. Donnelly. Physiological Carotid Body Denervation During Aging; C. Di Giulio, J. Aantosiewicz, M. Walski, G. Petruccelli, C.Di Giulio, V. Verratti, G. Bianchi and M. Pokorski. Does Ageing Modify Ventilatory Responses to Dopamine in Anaesthetised Rats Breathing Spontaneously? T.C. Monteiro1, A. Obeso, C. Gonzalez and, E.C. Monteiro. The Role of the Carotid Bodies in the Counter-Regulatory Response to Hypoglycemia; Denham S. Ward, MD, PHD; William A. Voter, MS; Suzanne Karan, MD. The Respiratory Responses to the Combined Activation of the Muscle Metaboreflex and the Ventilatory Chemoreflex; C.K. Lykidis, P. Kumar and G.M. Balanos. Cardiovascular Responses to Hyperoxic Withdrawal of ArterialChemosensory Drive; Patricio Zapata, Carolina Larrain, Marco-Antonio Rivera and Christian Calderón. Time-Dependence of Hyperoxia-Induced Impairment in Peripheral Chemoreceptor Activity and Glomus Cell Calcium Response; J.L. Carroll, I. Kim, H. Dbouk, D.J. Yang, R.W. Bavis and D.F. Donnelly. Long-term Regulation of Carotid Body Function: Acclimatization and Adaptation. Invited article; N. R. Prabhakar, Y.-J. Peng, G. K. Kumar, J. Nanduri, C. DI Giulio, Sukhamay Lahiri. Effects of Intermittent Hypoxia on Blood Gases Plasma Catecholamine and Blood Pressure; González-Martín, M.C., Vea-Agapito, V., Agapito, M.T., Castañeda, J. and González, C. Cardioventilatory Aclimatization Induced by Chronic Intermittent Hypoxia; R. Iturriaga, S. Rey, R. Del Rio, E.A. Moya, and J. Alcayaga. Ventilatory Drive is Enhanced in Male and Female Rats Following Chronic Intermittent Hypoxia; D. Edge, J.R. Skelly, A. Bradford, K.D. O'Halloran. Contrasting Effects of Intermittent and Continuous Hypoxia on Low O2 Evoked Catecholamine Secretion from Neonatal Rat Chromaffin Cells; Dangjai Souvannakitti, Ganesh K. Kumar, Aaron Fox and Nanduri R.Prabhakar. Hypoxic Pulmonary Vasoconstriction. Invited article; A. Mark Evans and Jeremy P.T. Ward. Impact of Modulators of Mitochondrial ATP-Sensitive Potassium Channel (mitoKATP) on Hypoxic Pulmonary Vasoconstriction; R. Paddenberg, P. Faulhammer, A. Goldenberg, B. Gries, J. Heinl, W. Kummer. Oxygen sensing in the brain. Invited article; Frank L. Powell, Cindy B. Kim, Randall S. Johnson, Zhenxing Fu. The Central Respiratory Chemoreceptor: Where is it Located? Invited article; Y. Okada, S. Kuwana, Z. Chen, M. Ishiguro and Y. Oku. Anatomical Architecture and Responses to Acidosis of a Novel Respiratory Neuron Group in the High Cervical Spinal Cord (HCRG) of the Neonatal Rat; Y. Okada, S. Yokota, Y. Shinozaki, R. Aoyama, Y. Yasui, M. Ishiguro and Y. Oku. Systemic Inhibition of the Na+/H+ Exchanger Type 3 in Intact Rats Activates Brainstem Respiratory Regions; R. Pasaro, J.L. Ribas-Salgueiro, E.R. Matarredona, M. Sarmiento, J. Ribas. Nitric Oxide in the Solitary Tract Nucleus (STn) Modulates Glucose Homeostasis and Fos-ir Expression after Carotid Chemoreceptor Stimulation; M. Lemus, S. Montero, S. Luquín, J. García and E.Roces de Álvarez-Buylla. Airway Receptors and Their Reflex Function. Invited article; J. Yu. Airway Chemosensitive Receptors in Vagus Nerve Perform Neuro-Immune Interaction for Lung-Brain Communicatio; H.F. Li and J. Yu. The role of NOX2 and "novel oxidases"in Airway Chemoreceptor O2 sensing; Ernest Cutz, Jie Pan and Herman Yeger. Recruitment of GABAA Receptors in Chemoreceptor Pulmonary Neuroepithelial Bodies by Prenatal Nicotine Exposure in Monkey Lung; XW. Fu and E.R. Spindel.Concluding Remarks. Index.