Papers presented at the first US Army Natick Research, Development and Engineering Center Symposium on [title], held in Natick, Mass., June 1993. The various symposium topics included application of AFM/STM in material sciences, polymers, physics, biology and biotechnology, along with recent developments including new probe microscopies. The proceedings are divided into three major parts: biological nanostructure, nanostructure of materials, and methodologies and techniques. The keynote address is Materials Research Instrument Development: A New Paradigm, by J.H. Hopps. Annotation c. by Book News, Inc., Portland, Or.