Autism Spectrum Disorders

Hardcover | June 20, 2011

EditorDavid Amaral, Daniel Geschwind, Geraldine Dawson

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Autism is an emerging area of basic and clinical research, and has only recently been recognized as a major topic in biomedical research. Approximately 1 in 150 children are diagnosed as autistic, so it is also an intense growth area in behavioral and educational treatments. Financialresources have begun to be raised for more comprehensive research and an increasing number of scientists are becoming involved in autism research. In many respects, autism has become a model for conducting translational research on a psychiatric disorder. This text provides a comprehensive summary of all current knowledge related to the behavioral, experiential, and biomedical features of the autism spectrum disorders including majorbehavioral and cognitive syndromology, common co-morbid conditions, neuropathology, neuroimmunology, and other neurological correlates such as seizures, allergy and immunology, gastroenterology, infectious disease, and epidemiology.Edited by three leading researchers, this volume contains over 80 chapters and nine shorter commentaries by thought leaders in the field, making the book a virtual "who's who" of autism research. This carefully developed book is a comprehensive and authoritative reference for what we know in thisarea as well as a guidepost for the next several years in all areas of autism research.

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Autism is an emerging area of basic and clinical research, and has only recently been recognized as a major topic in biomedical research. Approximately 1 in 150 children are diagnosed as autistic, so it is also an intense growth area in behavioral and educational treatments. Financialresources have begun to be raised for more comprehe...

David Amaral is Professor of Psychiatry and Neuroscience, Beneto Foundation Chair and Research and Director of The M.I.N.D. Institute, University of California at Davis. Daniel Geschwind is Gordon and Virginia MacDonald Distinguished Professor of Neurology, Psychiatry and Human Genetics and Director, Center for Autism Research and Tre...

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Format:HardcoverDimensions:1520 pages, 11 × 8.5 × 0.98 inPublished:June 20, 2011Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0195371828

ISBN - 13:9780195371826

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Table of Contents

Isabelle Rapin: Introduction: Autism Turns 65: A Neurologist's Bird's Eye ViewSection I: Historical perspective, diagnosis and classification, and epidemiology1. Michael Rutter: Autism Spectrum Disorders: Looking Backward and Looking Forward2. Katherine Gotham, Somer L. Bishop, and Catherine Lord: Diagnosis of Autism Spectrum Disorders3. Ami Klin: Asperger's Syndrome: From Asperger to Modern Day4. Sally Ozonoff, Kelly Heung, and Meagan Thompson: Regression and Other Patterns of Onset5. Screening, Risk, and Early Identification of Autism Spectrum Disorders6. Epidemiology of Pervasive Developmental Disorders7. Roy Richard Grinker, Marshalyn Yeargin-Allsopp, and Coleen Boy: Culture and Autism Spectrum Disorders: The Impact on Prevalence and RecognitionPatrick Bolton: Commentary: Issues in the Classification of Pervasive Developmental DisordersSection II: Core features and developmental trajectories8. Peter Mundy: The Social Behavior of Autism: A Parallel and Distributed Information Processing Perspective9. Helen Tager-Flusberg, Lisa Edelson, and Rhiannon Luyster: Language and Communication in Autism Spectrum Disorders10. Wouter B. Groen and Jan K. Buitelaar: Cognitive and Neural Correlates of Language in Autism11. James W. Bodfish: Repetitive Behaviors in Individuals with Autism Spectrum Disorders12. Rebecca J. Landa: Developmental Features and Trajectories Associated with Autism Spectrum Disorders in Infants and Toddlers13. Tony Charman: Development from Preschool through School Age14. Marsha Mailick Seltzer, Jan S. Greenberg, Julie Lounds Taylor, Leann Smith, Gael I. Orsmond, Anna Esbensen, and Jinkuk Hong: Adolescents and Adults with Autism Spectrum DisordersKatherine A. Loveland: Commentary: Issues in Defining the Core Features of Autism through the LifespanSection III: Psychiatric and medical co-morbidities15. Elisabeth M. Dykens and Miriam Lense: Intellectual Disabilities and Autism Spectrum Disorder: A Cautionary Note16. Bonnie P. Taylor and Eric Hollander: Comorbid Obsessive-Compulsive Disorders17. Suma Jacob, Angeli Landeros-Weisenberger, and James F. Leckman: Interface between Autism Spectrum Disorders and Obsessive-Compulsive Behaviors: A Genetic and Developmental Perspective18. Angela M. Reiersen and Richard D. Todd: Attention-Deficit/Hyperactivity Disorder (ADHD)19. J. Bruce Tomblin, Karla McGregor, and Allison Bean: Specific Language Impairment20. Peter Szatmari and Beth McConnell: Anxiety and Mood Disorders in Individuals with Autism Spectrum Disorder21. Lindsey Sterling, Annie McLaughlin, and Bryan H. King: Stereotypy and Self-Injury22. Matthew W. Mosconi, Yukari Takarae, and John A. Sweeney: Motor Functioning and Dyspraxia in Autism Spectrum Disorders23. Roberto Tuchman: Epilepsy and Electroencephalography in Autism Spectrum Disorders24. Paula Goines, Andrew Zimmerman, Paul Ashwood, and Judy Van de Water: The Immune System, Autoimmunity, Allergy, and Autism Spectrum Disorders25. Timothy Buie: Gastrointestinal Problems in Individuals with Autism Spectrum Disorders26. Anne E. Porter and Daniel G. Glaze: Sleep ProblemsChristopher Gillberg: Commentary: Autism as a Medical DisorderSection IV: Broader autism phenotype27. Molly Losh, Ralph Adolphs, and Joseph Piven: The Broad Autism Phenotype28. Janet E. Lainhart and Nicholas Lange: The Biological Broader Autism Phenotype29. John N. Constantino: Autism as a Quantitative TraitJeremy R. Parr, Kerstin Wittemeyer, and Ann S. Le Couteur: Commentary: The Broader Autism Phenotype: Implications for Research and Clinical PracticeSection V: Neurobiology30. John L. R. Rubenstein: Developmental Neurobiology of Autism Spectrum Disorders31. Cynthia M. Schumann, Steven C. Noctor, and David G. Amaral: Neuropathology of Autism Spectrum Disorders: Postmortem Studies32. Diane C. Chugani: Neurotransmitters33. Stephen R. Dager, Neva M. Corrigan, Todd Richards, and Dennis Shaw: Brain Chemistry: Magnetic Resonance Spectroscopy34. Meera E. Modi and Larry J. Young: Oxytocin, Vasopressin, and Social Behavior: Implications for Autism Spectrum Disorders35. Eric Courchesne, Sara Jane Webb, and Cyndi Schumann: From Toddlers to Adults: The Changing Landscape of the Brain in Autism36. Nancy J. Minshew, K. Suzanne Scherf, Marlene Behrmann, and Katherine Humphreys: Autism as a Developmental Neurobiological Disorder: New Insights from Functional Neuroimaging37. Sara Jane Webb, Raphael Bernier, Karen Burner, and Michael Murias: Electrophysiological Research on AutismPat Levitt: Commentary: Toward a Neurobiology of AutismSection VI: Etiology: Genetics38. Janine A. Lamb: Whole Genome Linkage and Association Analyses39. Rita M. Cantor: Autism Endophenotypes and Quantitative Trait Loci40. Judith H. Miles: Autism Subgroups from a Medical Genetics Perspective41. Hande Kaymakcalan and Matthew W. State: Rare Genetic Variants and Autism Spectrum Disorders42. Richard Person, Xinna Zhang, Soeun Kim, Marwan Shinawi, and Arthur L. Beaudet: Known and Possible Roles of Epigenetics in Autism43. Karola Rehnstrom and Leena Peltonen: Isolated Populations and Common Variants44. Eric M. Morrow and Christopher A. Walsh: Isolate Populations and Rare Variation in Autism Spectrum Disorders45. Jeffrey L. Neul: Rett Syndrome and MECP2-Related Disorders46. Randi J. Hagerman, Vivien Narcisa, and Paul J. Hagerman: Fragile X: A Molecular and Treatment Model for Autism Spectrum DisordersDaniel H. Geschwind: Commentary: Autism Genetics and Genomics: A Brief Overview and SynthesisSection VII Etiology: Environmental factors47. Irva Hertz-Picciotto: Environmental Risk Factors in Autism: Results from Large-Scale Epidemiologic Studies48. Patricia M. Rodier: Environmental Exposures that Increase the Risk of Autism Spectrum Disorders49. Mark A. Corrales and Martha R. Herbert: Autism and Environmental Genomics: Synergistic Systems Approaches to Autism ComplexitySection VIII: Animal models and theoretical perspectives50. Alicia Blaker, Gianluca DeRienzo, and Hazel Sive: Zebrafish as a Tool to Study Autism51. Mu Yang, Maria Luisa Scattoni, Kathryn K. Chadman, Jill L. Silverman, and Jacqueline N. Crawley: Behavioral Evaluation of Genetic Mouse Models of Autism52. Elaine Hsiao, Catherine Bregere, Natalia Malkova, and Paul H. Patterson: Modeling Features of Autism in Rodents53. Melissa D. Bauman and David G. Amaral: Nonhuman Primate Models of Autism54. Rajesh K. Kana and Marcel Adam Just: Autism as a Disorder of Functional Brain Activity55. Simon Baron-Cohen, Bonnie Auyeung, Emma Ashwin, and Rebecca Knickmeyer: The Extreme Male Brain Theory of Autism: The Role of Fetal Androgens56. Marco Iacoboni: The Mirror Neuron System and Imitation57. Keith J. Yoder and Matthew K. Belmonte: Information Processing and IntegrationFrancesca Happe: Commentary: Translation between Different Types of ModelSection IX: Treatment approaches58. Tristam Smith: Applied Behavior Analysis and Early Intensive Behavioral Intervention59. Laura Schreibman and Brooke Ingersoll: Naturalistic Approaches to Early Behavioral Intervention60. Stanley I. Greenspan and Serena Wieder: Relationship-Based Early Intervention Approach to Autistic Spectrum Disorders: The DIR Model61. Sally J. Rogers and Katherine Wallace: Intervention for Infants and Toddlers with Autism Spectrum Disorders62. Lynn Kern Koegel, Rosy M. Fredeen, Robert L. Koegel, and C. Enjey Lin: Relationships, Independence, and Communication in Autism and Asperger's Disorder63. Linn Wakeford and Grace T. Baranek: Occupational Therapy64. Marjorie H. Charlop, Alissa L. Greenberg, and Gina T. Chang: Augmentative and Alternative Communication Systems65. Edward G. Carr: Positive Behavior Support and Problem Behavior66. Connie Kasari and Jill Locke: Social Skills Interventions for Children with Autism Spectrum Disorders67. Robin Gabriels: Adolescent Transition to Adulthood and Vocational Issues68. Annette Estes, Vanessa Hus, and Lauren Elder: Family Adaptive Functioning in Autism69. Kelly Blankenship, Craig A. Erickson, Kimberly A. Stigler, David J. Posey, and Christopher J. McDougle: Psychopharmacological Treatment of Autism70. Margaret L. Bauman: Autism Spectrum Disorders: Identification and Implications of Associated Medical Conditions71. Susan L. Hyman and Susan E. Levy: Dietary, Complementary, and Alternative Therapies72. Dilja D. Krueger and Mark F. Bear: The mGluR Theory of Fragile X SyndromeEvdokia Anagnostou, Mark F. Bear, and Geraldine Dawson: Commentary: Future Directions in the Treatment of Autism Spectrum DisordersSection X: Best practices in the diagnosis and treatment of autism73. Zachary Warren and Wendy L. Stone: Best Practices: Early Diagnosis and Psychological Assessment74. Daniel L. Coury: Diagnosis and Assessment of Autism Spectrum Disorders: A Medical Perspective75. Kara Hume and Samuel L. Odom: Best Practice, Policy, and Future Directions: Behavioral and Psychosocial Interventions76. James T. McCracken: Pharmacotherapy for Autism Spectrum Disorders77. Mary Catherine Aranda and Sarah J. Spence: Best Practices: PediatricsHolly K. Tabor: Commentary: Bioethical Considerations in Autism Research and Translation: Present and FutureSection XI: Public policy78. Djesika Amendah, Scott D. Grosse, Georgina Peacock, and David S. Mandell: The Economic Costs of Autism: A Review79. Thomas Insel and Susan A. Daniels: Future Directions: Setting Priorities to Guide the Federal Research Effort80. Peter H. Bell and Craig Snyder: "To Petition the Government for a Redress of Grievances": Introduction81. Temple Grandin: Top Priorities for Autism: Asperger's Research: Perspectives from a Person with Autism