Basement Membranes

Hardcover | November 23, 2015

byJeffrey H. MinerEditorJeffrey H. Miner

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Basement Membranes focuses on specialized extracellular matrices that provide the scaffolds used and required by cells to organize themselves into tissues and organs. As basement membranes have been shown to be defective in numerous genetic and acquired diseases and to contribute to the microenvironment of both tumor cells and stem cells, this book presents a view of specific basement membrane components and their roles in development and disease, all written and commented on in chapters written by leaders in the basement membrane field. Written by leading experts in the basement membrane field Contains original material, both textual and illustrative, that should become a very relevant reference material Presents material in a very comprehensive manner Ideal for both researchers in the field and general readers who will find relevant and up-to-date information

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Basement Membranes focuses on specialized extracellular matrices that provide the scaffolds used and required by cells to organize themselves into tissues and organs. As basement membranes have been shown to be defective in numerous genetic and acquired diseases and to contribute to the microenvironment of both tumor cells and stem cel...

Dr.Jeffrey H. Miner, PhD, received his doctorate in Molecular Biology and Biochemistry in 1991 from the California Institute of Technology in Pasadena, CA. In 1992 he moved to Washington University in St. Louis for postdoctoral training with Dr. Joshua R. Sanes. In 1996 he was appointed Assistant Professor of Medicine in the Washington...

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Format:HardcoverDimensions:404 pages, 9.41 × 7.24 × 0.98 inPublished:November 23, 2015Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0128040157

ISBN - 13:9780128040157

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Table of Contents

  1. Integrating Activities of Laminins that Drive Basement Membrane Assembly and Function
    Peter D. Yurchenco
  2. Laminin-a2 Chain-Deficient Congenital Muscular Dystrophy: Pathophysiology and Development of Treatment
    Madeleine Durbeej
  3. Type IV Collagens and Basement Membrane Diseases: Cell Biology and Pathogenic Mechanisms
    Mao Mao, Marcel V. Alavi, Cassandre Labelle-Dumais and Douglas B. Gould
  4. Epidermal Basement Membrane in Health and Disease
    Cristina Has and Alexander Nyström
  5. Applying Proteomics to Investigate Extracellular Matrix in Health and Disease
    Michael Randles and Rachel Lennon
  6. Molecular Basis of Laminin Integrin Interactions
    Masashi Yamada and Kiyotoshi Sekiguchi
  7. Cell Receptor-Basement Membrane Interactions in Health and Disease: A Kidney-Centric View
    Corina M. Borza, Xiwu Chen, Roy Zent and Ambra Pozzi
  8. The Basement Membrane Proteoglycans Perlecan and Agrin: Something Old& Something New
    Kevin J. McCarthy
  9. Building From the Ground Up: Basement Membranes inDrosophilaDevelopment
    Adam J. Isabella and Sally Horne-Badovinac
  10. Basement Membranes in the Worm: A Dynamic Scaffolding that Instructs Cellular Behaviors and Shapes Tissues
    Matthew R. Clay and David R. Sherwood