Biochemistry and Molecular Biology

Paperback | March 12, 2014

byDespo Papachristodoulou, Alison Snape, William H. Elliott

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Now in its fifth edition Biochemistry and Molecular Biology features a new author team, who have retained the much-praised clarity of previous editions, while adding a more biomedical focus and incorporating a discussion of recent developments in research. A new chapter on the general principles of nutrition emphasises the key principles underlying complex metabolic pathways, enabling students to appreciate an integrated view of human metabolism and nutrition. Also new to the fifth edition, a chapter on the control of gene expression reflects ourincreasing understanding of the importance and power of gene regulation. With an integrated approach covering both biochemistry and molecular biology, complemented by frequent diagrams and clear explanations, and all presented in a broader cellular context, this text is the perfect introduction for any student new to the subject.Online Resource Centre: The Online Resource Centre features: For registered adopters of the book: DT Figures from the book available to downloadFor students: DT Further reading organised by chapter, linked to the book via QR codesDT An extensive bank of multiple-choice questions for self-directed learningDT Links to 3D molecular structures

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From the Publisher

Now in its fifth edition Biochemistry and Molecular Biology features a new author team, who have retained the much-praised clarity of previous editions, while adding a more biomedical focus and incorporating a discussion of recent developments in research. A new chapter on the general principles of nutrition emphasises the key principl...

Dr Despo Papachristodoulou is Senior Lecturer in Biochemistry and also Head of Preclinical Medicine at King's College London. Her research interests include diabetes and diabetic complications, insulin metabolism, intermediary metabolism, nutrition, medical education, and curriculum development. Dr Alison Snape is Programme Director f...
Format:PaperbackDimensions:648 pages, 10.55 × 8.07 × 0.01 inPublished:March 12, 2014Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199609497

ISBN - 13:9780199609499

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Table of Contents

Part 1: Basic concepts of life1. The basic molecular themes of life2. Cells and viruses3. Energy considerations in biochemistryPart 2: Structure and function of proteins and membranes4. The structure of proteins5. Methods in protein investigation6. Enzymes7. The cell membrane and membrane proteins8. Muscle contraction, the cytoskeleton, and molecular motorsPart 3: Metabolism and Nutrition9. General principles of nutrition10. Food digestion, absorption, and distribution to the tissues11. Mechanisms of transport, storage, and mobilization of dietary components12. Principles of energy release from food13. Glycolysis, the TCA cycle, and the electron transport system14. Energy release from fat15. An alternative pathway of glucose oxidation. The pentose phosphate pathway16. Synthesis of glucose (gluconeogenesis)17. Synthesis of fat and related compounds18. Nitrogen metabolism: amino acid metabolism19. Nitrogen metabolism: nucleotide metabolism20. Mechanisms of metabolic control and their applications to metabolic integration21. Raising electrons of water back up the energy scale -- photosynthesisPart 4: Information storage and utilization22. The genome23. DNA synthesis, repair, and recombination24. Gene transcription25. Protein synthesis and controlled protein breakdown26. Control of gene expression27. Protein sorting and delivery28. Manipulating DNA and genesPart 5: Cells and tissues29. Cell signalling30. The cell cycle, cell division, and cell death31. CancerPart 6: Protective mechanisms against disease32. Special topics: blood clotting, xenobiotic metabolism, reactive oxygen species33. The immune system

Editorial Reviews

"The style is very clear, logical and systematic. The diagrams complement the text well" --Dr Momna Hejmadi, Department of Biology and Biochemistry, University of Bath