Bioinformatics and Drug Discovery by Richard S. LarsonBioinformatics and Drug Discovery by Richard S. Larson

Bioinformatics and Drug Discovery

EditorRichard S. Larson

Paperback | December 9, 2010

Pricing and Purchase Info

$260.34 online 
$271.95 list price
Earn 1302 plum® points

In stock online

Ships free on orders over $25

Not available in stores


A collection of readily reproducible bioinformatic methods to advance the drug discovery process from gene identification to protein modeling to the identification of specific drug candidates. The authors demonstrate these techniques, including microarray analysis, the analysis of genes as potential drug targets, virtual screening and in silico protein design, and cheminformatics, in a variety of practical situations. Because these technologies are still emergent, each chapter contains an extended introduction that explains the theory and application of the technology and techniques described.
Title:Bioinformatics and Drug DiscoveryFormat:PaperbackDimensions:454 pages, 9.02 × 5.98 × 0 inPublished:December 9, 2010Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617375098

ISBN - 13:9781617375095

Look for similar items by category:


Table of Contents

New Strategies in Drug DiscoveryEliot H. Ohlstein, Anthony G. Johnson, John D. Elliot, and Anne M. RomanicBasic Microarray Analysis: Strategies for Successful ExperimentsScott A. NessFrom Microarray to Biological Networks: Analysis of Gene Expression ProfilesXiwei Wu and T. Gregory DeweyMicroarray Analysis in Drug Discovery and Clinical ApplicationsSiqun Wang and Qiong ChengOntology-Driven Approaches to Analyzing Data in Functional GenomicsFrancisco Azuaje, Fatima Al-Shahrour, and Joaquin DopazoGene Evolution and Drug DiscoveryJames O. McInerney, Caroline S. Finnerty, Jennifer M. Commins, and Gayle K. PhilipStandardization of Microarray and Pharmacogenomics DataCasey S. Husser, Jeffrey R. Buchhalter, O. Scott Raffo, Amnon Shabo, Steven H. Brown, Karen E. Lee, and Peter L. ElkinClinical Applications of Bioinformatics, Genomics, and PharmacogenomicsOmer Iqbal and Jawed FareedProtein Interactions Probed With Mass SpectrometrySuma Kaveti and John R. EngenDiscovering New Drug Targeting Sites on Flexible Multidomain Protein Kinases: Combining Segmental Isotopic and Site-Directed Spin Labeling for Nuclear Magnetic Resonance Dectection of Interfacial CleftsThomas K. HarrisNuclear Magnetic Resonance-Based Screening Methods for Drug DiscoveryLaurel O. Sillerud and Richard S. LarsonReceptor-Binding Sites: Bioinformatic ApproachesDarren R. FlowerIn Silico Protein Design: Fitting Sequence Onto StructureBassil I. DahiyatChemical Database Preparation for Compound Acquisition or Virtual ScreeningCristian G. Bologna, Marius M. Olah, and Tudor I. OpreaBioinformatics Platform Development: From Gene to Lead CompoundAlexis S. Ivanov, Alexander V. Veselovsky, Alexander V. Dubanov, and Vladlen S. SkvortsovIndex

Editorial Reviews

"...succeeds admirably in illuminating the latest interdisciplinary techniques being applied to drug discovery, including target selection and validation, receptor binding site characterization and binding prediction, and use for new lead discovery." - Journal of Medicinal Chemistry