Bioinorganic Chemistry by Dieter RehderBioinorganic Chemistry by Dieter Rehder

Bioinorganic Chemistry

byDieter Rehder

Paperback | January 24, 2014

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Bioinorganic chemistry lies at the interface of inorganic chemistry and biochemistry, and explores the function of inorganic species in living systems - from the iron that helps our red blood cells transport oxygen to our tissues, to the calcium that forms an integral part of our bones. In his book, Rehder provides a broad overview of this dynamic field, reviewing the key chemical elements that have important biological function, and exploring how the chemistry of these elements is central to the function of biological systems. With sidebars that both review underlying principles of importance to the subject - including the concepts of magnetism and chirality - and discuss some of the analytical approaches that have enabled us to elucidate the biological role of the chemical elements, Bioinorganic Chemistry is the idealresource for those discovering the field for the first time, and who need a clear, balanced account of the subject. Online Resource CentreThe Online Resource Centre to accompany Bioinorganic Chemistry features figures from the book in electronic format, for use in lecture slides and other teaching materials.
Dieter Rehder is a Professor in the Institute of Inorganic and Applied Chemistry, University of Hamburg where his main fields of research include organometallic, bioinorganic and medicinal chemistry (of vanadium), oxido- and sulfidometal clusters, and metal NMR. Dieter was winner of the Vanadis Award 2006 for outstanding research in th...
Title:Bioinorganic ChemistryFormat:PaperbackDimensions:240 pages, 9.69 × 7.44 × 0.03 inPublished:January 24, 2014Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199655197

ISBN - 13:9780199655199

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Table of Contents

Introduction1. Bio-Elements in the Periodic Table2. Pre-Life and Early Life Forms; extremophiles3. The Alkaline and Alkaline Earth Metals3.1 Overview3.2 Ion Channels3.3 Sodium and Potassium3.4 Magnesium3.5 Calcium4. Iron: General Features of its Inorganic Chemistry and Biochemistry4.1 General, and Aqueous Chemistry4.2 Mobilization, Transport, Delivery, and Mineralization of Iron5. Oxygen Transport and the Respiratory Chain5.1 Oxygen and oxygen transport by haemoglobin and myoglobin5.2 Oxygen transport by hemerythrin and haemocyanin5.3 The Respiratory Chain6. Oxidoreductases Based on Iron, Manganese, and Copper6.1 Ribonucleotide Reductases6.2 Superoxide dismutases, superoxide Reductases, and peroxidases6.3 Oxygenases and oxidases7. Oxo-transfer Proteins Based on Molybdenum, Tungsten, and Vanadium7.1 Molybdo- and Tungsto-pyranopterins7.1.1 The Xanthine Oxidase Family7.1.2 The Sulfite Oxidase Family7.1.3 The Dimethylsulfoxide (DMSO) Reductase Family7.2 Vanadate-dependent Haloperoxidases7.3 Model Chemistry8. The Sulfur Cycle8.1 Environmental Sulfur Cycling8.2 Biogenic Metabolism of Sulfur9. Nitrogenase and Nitrogen Cycle Enzymes9.1 Overview and Native Nitrogenase9.2 Nitrogenase Models and Model Reactions9.3 Denitrification9.4 Nitric Oxide10. The Methane Cycle and Nickel Enzymes10.1 Introduction10.2 Methanogenesis10.3 Biogenic Oxidation of Methane10.4 Nickel Enzymes not Involved in Methane Metabolism11. Photosynthesis11.1 Overview11.2 The Reaction Pathway11.3 Modeling Photosynthesis12. The Biochemistry of Zinc12.1 An Overview of Zinc12.2 Zinc Enzymes12.2.1 Carboanhydrases12.2.2 Hydrolases12.2.3 Alcohol Dehydrogenase12.3 The Role of Zinc in the Transcription of Genes12.4 Thioneins13. Metal- and Metalloid-Carbon Bonds13.1 Organometallic Compounds of Transition Metals13.2 Carbon Bonds to Main Group Metals and Metalloids14. Inorganics in Medicine14.1 Metals and Metalloids: An Introduction14.2 Dysfunction of Iron and Copper Homeostasis14.2.1 Iron14.2.2 Copper14.3 Metals and Metalloids in Therapy14.3.1 Historical and General Notes14.3.2 Treatment of Arthritis with Gold Compounds14.3.3 Cancer Treatment14.3.4 Further Metal Based Medications14.3.5 Radiopharmaceuticals14.4 Metals and Metalloids in Diagnostic Imaging14.5 The Toxic and Therapeutic Potential of CO, NO and H2S