Biology Of Aggression

Hardcover | August 25, 2005

EditorRandy J. Nelson

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Unchecked aggression and violence take a significant toll on society. Even if we manage to avoid being the direct victim of a violent act, the effects of aggression and violence reach us all: We hear about the mauling of a woman by an aggressive dog, our children are bullied at school, or wedeal with impulsive violence while commuting to work or attending a sporting event. Reflecting psychology in general, the dominant roles of learning and environmental influences - both social and nonsocial - have traditionally been prominent in discussions of the etiology of human aggression.Biological factors have not been considered sufficiently important to investigate in the search for ways of dealing with human aggression or violence. With recent advances in pharmacology and genetic manipulation techniques, however, new interest has developed in the biological mechanisms of bothnon-human and human aggression. Although aggression is certainly a complex social behavior with multiple causes, molecular biological factors should not be overlooked, as they may well lead to interventions that prevent excess aggressive behaviors. The primary goal of this book is to summarize andsynthesize recent advances in the biological study of aggression. As most aggressive encounters among human and non-human animals represent a male proclivity, the research in this book describes and discusses studies using the most appropriate murine model: testosterone-dependent offensiveinter-male aggression, which is typically measured in resident-intruder or isolation-induced aggression tests. The research also emphasizes various molecules that have been linked to aggression tests. The research also emphasizes various molecules that have been linked to aggression by the latestgene-targeting and pharmacological techniques. Although the evidence continues to point to androgens and serotonin (5-HT) as major hormonal and neurotransmitter factors in aggressive behavior, recent work with GABA, dopamine, vasopressin, and other factors, such as nitric oxide, has revealedsignificant interactions with the neural circuitry underlying aggression. This book is organized according to levels of analysis. The first section examines the genetic contributions to aggression in species ranging from crustaceans to humans. The section summarizes the involvement of variousneurotransmitters and neuromodulators in aggressive behavior. The third section summarizes the influence of hormones on aggression, primarily in humans. All chapters emphasize future directions for research on aggression and reveal important domains that have received comparatively less attentionin this literature. Considered together, these chapters provide up-to-date coverage of the biology of aggression by some of the leading authorities currently working in this field. Biology of Aggression will direct future research to continue the recent advances in the pharmacological and geneticapproaches to understanding aggression and violence. It promises to be a valuable resource for professional and student researchers in neuroscience, psychiatry, cognitive and developmental psychology, behavioral biology, and veterinary medicine.

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Unchecked aggression and violence take a significant toll on society. Even if we manage to avoid being the direct victim of a violent act, the effects of aggression and violence reach us all: We hear about the mauling of a woman by an aggressive dog, our children are bullied at school, or wedeal with impulsive violence while commuting...

Randy J. Nelson is at Ohio State University.

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Format:HardcoverDimensions:528 pages, 6.89 × 10.12 × 1.1 inPublished:August 25, 2005Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0195168763

ISBN - 13:9780195168761

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Table of Contents

Section 1. GenesChapter 1. Genetic Aspects of Aggression in Nonhuman AnimalsChapter 2. Human Quantitative Genetics of AggressionChapter 3. Crustacean Models of AggressionSection 2. NeurotransmittersChapter 4. Brain Serotonin and Aggressive Disposition in Humans and Non-human PrimatesChapter 5. Monoamines, GABA, Glutamate, and AggressionChapter 6. Nitric Oxide and AggressionChapter 7. Neuropeptides and AggressionSection 3 . HormonesChapter 8. Contexts and Ethology of Vertebrate Aggression: Implications for the Evolution of Hormone Behavior InteractionsChapter 9. Androgens and AggressionChapter 10. The Role of Estrogen Receptors in the Regulation of Aggressive BehaviorsChapter 11. Maternal AggressionChapter 12. Stress and Aggressive BehaviorsStress 4. DevelopmentChapter 13. Conditioned DefeatChapter 14. Development of AggressionChapter 15. Neurobiology of Aggression in ChildrenSection 5 . Pharmacology and PsychophysiologyChapter 16. Drugs of Abuse and AggressionChapter 17. Psychopharmacology of Human Aggression: Laboratory and Clinical StudiesChapter 18. Psychophysiology of Human Antisocial Behavior

Editorial Reviews

"This timely volume covers genetics, neurotransmitters, hormones, development, pharmacology and psychophysiology. Almost all the chapters are up to date, point out weaknesses in previous investigations and suggest future directionsa real help to the novice in this area. Of course, oneprincipal reason that neuroscientists study aggression is to learn how to modulate it in humans and perhaps how to cope with it in other species. This book provides a good yardstick to measure where we stand in attaining those goals, while making clear that we are not yet able to predict with anyuseful degree of precision who will be aggressive and when they will be aggressive . . . Studying the key variables identified in this book may help reduce aggression and recidivism in the adolescent and adult violent population, as well as persistent bullying at school." --Jordan Grafman, MarenStrezniak, and Frank Krueger in Nature Neuroscience