Biology Of Negative Strand Rna Viruses: The Power Of Reverse Genetics by Yoshihiro KawaokaBiology Of Negative Strand Rna Viruses: The Power Of Reverse Genetics by Yoshihiro Kawaoka

Biology Of Negative Strand Rna Viruses: The Power Of Reverse Genetics

EditorYoshihiro Kawaoka

Hardcover | May 7, 2004

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Negative-strand RNA viruses, so named because of the polarity of their genomic RNA to mRNA, include important human and non-human pathogens. This volume covers major advances in reverse genetics techniques over the past decade, state-of-the-art basic science and the clinical implications of experimental findings. This should rekindle interest in negative-strand RNA viruses among readers, including those in other disciplines, leading to further progress in understanding these important viruses and in developing effective measures of control.

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Title:Biology Of Negative Strand Rna Viruses: The Power Of Reverse GeneticsFormat:HardcoverDimensions:359 pages, 9.25 × 6.1 × 0.09 inPublished:May 7, 2004Publisher:Springer Berlin HeidelbergLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3540406611

ISBN - 13:9783540406617

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Table of Contents

Introduction.- Reverse genetics of mononegavirales.- Reverse systems for the generation of segmented negative-sense RNA viruses entirely from cloned cDNA.- Transcription and replication of non-segmented negative strand RNA viruses.- Orthomyxovirus replication, transcription, and polyadenylation.- Escaping from the cell: assembly and budding of negative-strand RNA viruses.- Accessory genes of the paramyxoviridae, a large family of nonsegmented negative strand RNA viruses, as a focus of active investigation by reverse genetics.- Identification and characterization of viral antagonists of type I interferon in negative-strand RNA viruses.- Towards multivalent vaccines and therapeutic viruses.- Influenza vaccines generated by reverse genetics.- Subject index