Biomechanics and Cells by Fiona LyallBiomechanics and Cells by Fiona Lyall

Biomechanics and Cells

EditorFiona Lyall, A. J. El Haj

Paperback | June 25, 2009

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This volume draws together these apparently disparate observations and makes comparisons among the nature of the cellular responses. Studies of cells derived from skeletal muscle, bone and cardiovascular tissue provide a comprehensive synthesis and review of recent work.
Title:Biomechanics and CellsFormat:PaperbackDimensions:288 pages, 9.02 × 5.98 × 0.63 inPublished:June 25, 2009Publisher:Cambridge University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0521114543

ISBN - 13:9780521114547


Table of Contents

Preface; Part I. Soft Tissue: 1. Signal transduction in vascular cells exposed to cyclic strain; 2. Effects of pressure overload on vascular smooth muscle cells; 3. Effect of increased flow on release of vasoactive substances from vascular endothelial cells; 4. Modulation of endothelium derived relaxing factor activity by flow; 5. Stretch, overload and gene expression in muscle; 6. Stretch sensitivity in stretch receptor muscles; 7. Mechanical interactions with plant cells - a selective overview; 8. Mechanical tensing of cells and chromosome arrangement; 9. Alterations in gene expression induced by low-frequency, low-intensity electromagnetic fields; Part II. Hard Tissue: 10. Cellular modelling of mechanical interactions with the skeleton; 11. Mechanical and hormonal influences in vivo cause regional differences in bone remodelling; 12. Mechanically sensitive cells in bone; 13. Mechanical stress and bone development; 14. Applications of homogenous, defined strains to cell cultures; 15. The role of prostaglandin in bone cells as mediators of mechanical strain; 16. Effects of mechanical stretch on actin polymerisation in fibroblasts of the periodontium; 17. Modulation of cartilage extracellular matrix turnover by pulsed electromagnetic fields; Index.

Editorial Reviews

"The strengths of this book include the diversity of cell types and physiological responses covered, the significant detail on the putative biological mechanisms by which mechanical stimuli may be transduced by cells, and most of all the variety and detail of the experimental models, preparations, and devices that are interesting collection of articles on mechanical signal transduction by cells in a variety of experimental settings." A.D. McCulloch, Applied Mechanics Review