Biomolecular NMR Spectroscopy

Paperback | May 1, 1995

byJeremy N. S. Evans

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The technique of nuclear magnetic resonance (NMR) spectroscopy is an important tool in biochemistry and biophysics for the understanding of the structure and ultimately, the function of biomolecules. This textbook explains the salient features of biological NMR spectroscopy to undergraduatesand postgraduates taking courses in NMR, biological NMR, physical biochemistry, and biophysics. Unlike other books in the general field of NMR (except the advanced treatises), the approach here is to introduce and make use of quantum mechanical product operators as well as the classical vectormethod of explaining the bewildering array of pulse sequences available today. The book covers two- dimensional, three- dimensional, and four- dimensional NMR and their application to protein and DNA structure determination. A unique feature is the coverage of the biological aspects of solid- stateNMR spectroscopy. The author provides many selected examples from the research literature, illustrating the applications of NMR spectroscopy to biological proteins.

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The technique of nuclear magnetic resonance (NMR) spectroscopy is an important tool in biochemistry and biophysics for the understanding of the structure and ultimately, the function of biomolecules. This textbook explains the salient features of biological NMR spectroscopy to undergraduatesand postgraduates taking courses in NMR, biol...

Jeremy N. S. Evans is at Washington State University, Pullman.

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Format:PaperbackDimensions:460 pages, 9.69 × 7.44 × 1.02 inPublished:May 1, 1995Publisher:Oxford University Press

The following ISBNs are associated with this title:

ISBN - 10:0198547668

ISBN - 13:9780198547662

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Table of Contents

Part 1: TheoryIntroduction1. Methods for spectral assignment - multidimensional NMR2. Obtaining NMR structuresPart II: Proteins3. Protein structure4. Protein foldingPart III: Enzymes5. Enzyme function6. Acyl and phosphoryl transfer enzymes7. Other enzymesPart IV: Nucleic Acids and Carbohydrates8. Nucleic acids and carbohydratesPart V: Membranes9. Structure of membranes and membrane proteinsAppendix 1 Examples of product operator calculationsAppendix 2 Useful NMR data on amino acid residuesAppendix 3 Useful NMR data on oligonucleotide residuesAppendix 4 Useful NMR data on common solventsIndex

Editorial Reviews

`The author writes clearly and enthusiastically ... the strength of the book is its broad coverage of scores of applications of NMR to important biological problems ... Another positive aspect of Biomolecular NMR Spectroscopy is the care with which the author places NMR in the context of thelarger scientific picture.'Patricia J. Lodi, nature structular biology volume 3 number 5 may 1996