Bioorganic Chemistry: Carbohydrates: Carbohydrates by Sidney M. HechtBioorganic Chemistry: Carbohydrates: Carbohydrates by Sidney M. Hecht

Bioorganic Chemistry: Carbohydrates: Carbohydrates

EditorSidney M. Hecht

Hardcover | August 1, 1998

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Bioorganic chemistry has expanded rapidly over the past two decades, enriching the disciplines of biology and chemistry and providing important insights into the workings of biological systems at a molecular level. Recently, this growing field has witnessed some very exciting results inapplying design and synthesis techniques to many problems in biochemistry and molecular biology. Bridging the gap between chemistry and biology, Topics in Bioorganic and Biological Chemistry: A Series of Books in Support of Teaching and Research will serve the needs of the many graduate students andresearchers who work in and study this discipline. The inaugural work in this series, Bioorganic Chemistry, is composed of three volumes: Nucleic Acids, Peptides and Proteins, and Carbohydrates. This third volume, Bioorganic Chemistry: Carbohydrates, provides a broad overview of the topic. It covers the chemical and enzymatic synthesis ofsimple and complex carbohydrates and modern methods for the analysis of carbohydrate structure, and reviews the ways in which carbohydrates mediate binding to cells and subcellular targets such as DNA, proteins, and antibody binding sites. It also provides an overview of cyclodextrins and theirproperties and the biosynthesis of carbohydrates. The text is comprised of 13 chapters, making it ideal for use in a one-semester graduate level special topics course in carbohydrates. Each chapter begins with an introduction that includes basic principles, a summary of key findings which support current research in the field, and an overview of current research activity. The remainder of each chapter deals in greater detail with a number of recent studies that illustratethe nature of ongoing activity in the field. All chapters have been written by leading researchers, and numerous references are given.
Sidney M. Hecht is at University of Virginia.
Title:Bioorganic Chemistry: Carbohydrates: CarbohydratesFormat:HardcoverPublished:August 1, 1998Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0195084691

ISBN - 13:9780195084696


Table of Contents

Ray Lemieux: ForewordPrefaceContributors1. Marcos Sznaidman: Introduction to Carbohydrates2. Andrea Vasella: Glycosylidene Carbenes3. Bert Fraser-Reid, Robert Madsen, A. Stewart Campbell, Carmichael S. Roberts, and J. Robert Merritt: Chemical Synthesis of Oligosaccharides4. K.C. Nicolaou and Nicholas J. Bockovich: Chemical Synthesis of Complex Carbohydrates5. Daniel Kahne, Domingos Silva, and Suzanne Walker: DNA-Binding Glycoconjugates6. Martin Hendrix and Chi-Huey Wong: Enzymatic Synthesis of Carbohydrates7. Anthony S. Serianni: Carbohydrate Structure, Conformation, and Reactivity: NMR Studies with Stable Isotopes8. Diane Hollenbaugh, Jurgen Bajorath, and Alejandro Aruffo: Cell Adhesion Molecules and Their Cellular Targets9. Francois Tropper and Mark Bednarski: Models of Cell Surface Carbohydrates and Biological Adhesion10. David R. Bundle: Recognition of Carbohydrate Antigens by Antibody Binding Sites11. Florante A. Quiocho and Nand K. Vyas: Atomic Interactions Between Proteins/Enzymes and Carbohydrates12. Dominique Armspach, Giuseppe Gattuso, Rainer Koniger, and J. Fraser Stoddart: Cyclodextrins13. Jac Preiss: Biosynthesis of Bacterial and Mammalian Glycogen and Plant Starch Synthesis and Their RegulationReferencesIndex