Cancer Biology

Paperback | April 9, 2007

byRaymond W. Ruddon

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A thorough yet concise account of cancer biology, this book emphasizes the cellular and molecular mechanisms involved in the transformation of normal into malignant cells, the invasiveness of cancer cells into host tissues, and the metastatic spread of cancer cells in the host organism. Italso defines the fundamental pathophysiological changes that occur in tumor tissue and in the host animal or patient. The approach throughout the book is to discuss the historical development of a field, citing the key experimental advances to the present day, and to evaluate the current evidencethat best supports or rules out concepts of the molecular and cellular mechanisms regulating cancer cell behavior. For all the areas of fundamental cancer research, an effort has been made to relate basic research findings to the clinical disease states. The book is well illustrated with schematicdiagrams and actual research data to demonstrate points made in the text, and there is an extensive, up-to-date bibliography. In this revision, Dr. Ruddon has organized his text to provide more integrated discussion of the many topics covered in the third edition. At the same time, he has included much new material on molecular genetics and genetic diagnosis (e.g., DNA microarrays to mark tumors), RNA interference, stemcells, cell cycle regulation, angiogenesis, etc.

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From the Publisher

A thorough yet concise account of cancer biology, this book emphasizes the cellular and molecular mechanisms involved in the transformation of normal into malignant cells, the invasiveness of cancer cells into host tissues, and the metastatic spread of cancer cells in the host organism. Italso defines the fundamental pathophysiological...

Raymond W. Ruddon is at Johnson and Johnson.

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Kobo ebook|Dec 6 2012

$112.69 online$146.27list price(save 22%)
Format:PaperbackDimensions:568 pages, 7.01 × 10 × 1.3 inPublished:April 9, 2007Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0195175441

ISBN - 13:9780195175448

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Table of Contents

1. Characteristics of Human Cancer2. Causes of Cancer3. The Epidemiology of Human Cancer4. The Biochemistry and Cell Biology of Cancer5. Molecular Genetics of Cancer6. Tumor Immunology7. Cancer Diagnosis8. Sequelae of Cancer and Its Treatment9. Cancer PreventionIndex

Editorial Reviews

"Provides a thorough, yet concise review of the cellular and molecular mechanisms involved in the transformation of normal into malignant cells...Clearly written and well illustrated, there is also an extensive, up-to-date bibliography, making the book valuable to basic scientists, physicians,nurses, and students interested in the field."--Anticancer Research