Capillary Electrophoresis Methods for Pharmaceutical Analysis by Satinder AhujaCapillary Electrophoresis Methods for Pharmaceutical Analysis by Satinder Ahuja

Capillary Electrophoresis Methods for Pharmaceutical Analysis

bySatinder AhujaEditorMohamedilias Jimidar

Hardcover | August 5, 2008

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Capillary electrophoresis (CE) is a powerful analytical technique that is widely used in research and development and in quality control of pharmaceuticals. Many reports of highly efficient separations and methods have been published over the past 15 years. CE offers several advantages over high-pressure or high-performance liquid chromatography (HPLC). These include simplicity, rapid analysis, automation, ruggedness, different mechanisms for selectivity, and low cost. Moreover, EC requires smaller sample size and yet offers higher efficiency and thus greater resolution power over HPLC. These characteristics are very attractive in research and development, even more so in pharmaceutical quality control (QC) and stability monitoring (SM) studies. This book will provide busy pharmaceutical scientists a complete yet concise reference guide for utilizing the versatility of CE in new drug development and quality control.

- Provides current status and future developments in CE analysis of pharmaceuticals.
- Explains how to develop and validate methods.
- Includes major pharmaceutical applications including assays and impurity testing.
Dr. Satinder Ahuja is a leading expert on improving water quality. He earned his PhD in analytical chemistry from the University of the Sciences, Philadelphia. He worked for Novartis Corp. in various leadership positions for over 25 years while simultaneously teaching and guiding research as an adjunct professor at Pace University for ...
Title:Capillary Electrophoresis Methods for Pharmaceutical AnalysisFormat:HardcoverDimensions:546 pages, 9.45 × 6.5 × 0.98 inPublished:August 5, 2008Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0123725739

ISBN - 13:9780123725738

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Table of Contents

1. Overview of Capillary Electrophoresis in Pharmaceutical Analysis
2. Theoretical Consideration in Performance of Various Modes of CE
3. Equipment Considerations for Capillary Electrophoresis
4. Method Development for Pharmaceutical Analysis
5. Role of CE in Drug Substance and Drug Product Development
6. General Considerations to Improve Performance of CE Methods
7. Overview of Current Regulatory Guidance
8. Qualification of CE Instrumentation
9. Robustness Testing of CE Methods
10. Validation of Analytical Methods
11. The Need for CE Methods in Pharmacopeial Monographs
12. CE in Impurity Profiling of Drugs
13. Ion Analysis
14. Role of CE in Biopharmaceutical Development and Quality Control
15. Capillary Electrophoresis and Bioanalysis
16. CE as Orthogonal Technique to Chromatography
17. Capillary Electrochromatography of Pharmaceuticals
18. Coupling CE and Chip-based Devices and Mass Spectrometry