Carbohydrate-based Interactions At The Molecular And The Cellular Level

June 5, 2018|
Carbohydrate-based Interactions At The Molecular And The Cellular Level by Kieran L. Hudson
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This book offers a clearly written and highly accessible account of two different aspects of carbohydrate chemistry. Carbohydrates are an essential component of life and have many important biological functions, but the details of how carbohydrates interact with other biomolecules to mediate biological signalling remain unclear. Firstly, this thesis details innovative methods to mine protein structural data to uncover new features of carbohydrate-based interactions. It also explains these findings using physical chemistry, specifically CH-pi interactions associated with the properties of the interacting partners. 

Carbohydrates are also critical for tissue growth and development, yet are underexploited in the materials science that underpins much of regenerative medicine. As such, the second part of this thesis describes a diverse array of techniques ranging from synthetic chemistry and enzymatic synthesis to prepare a wide variety of carbohydrates, and materials chemistry to prepare glycosylated hydrogels, to cell biology to determine the effects on cellular development for tissue engineering applications.

Dr Kieran Hudson received a Master of Chemistry degree from the University of Oxford, UK in 2011. During his research there he developed an interest in the intersection of chemistry and biology, particularly in how small structural differences in biomolecules have substantial effects in nature. He developed this interest during his pos...
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Title:Carbohydrate-based Interactions At The Molecular And The Cellular Level
Format:Hardcover
Product dimensions:198 pages, 9.25 X 6.1 X 0 in
Shipping dimensions:198 pages, 9.25 X 6.1 X 0 in
Published:June 5, 2018
Publisher:Springer Nature
Language:English
Appropriate for ages:All ages
ISBN - 13:9783319777054

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