Cardiac Repolarization: Bridging Basic and Clinical Science by Ihor GussakCardiac Repolarization: Bridging Basic and Clinical Science by Ihor Gussak

Cardiac Repolarization: Bridging Basic and Clinical Science

EditorIhor Gussak

Paperback | November 9, 2010

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A comprehensive review of all the latest developments in cardiac electrophysiology, focusing on both the clinical and experimental aspects of ventricular repolarization, including newly discovered clinical repolarization syndromes, electrocardiographic phenomena, and their correlation with the most recent advances in basic science. The authors illuminate the basic electrophysiologic, molecular, and pharmacologic mechanisms underlying ventricular repolarization, relate them to specific disease conditions, and examine the future of antiarrhythmic drug development based on both molecular and electrophysiological properties. They also fully review the clinical presentation and management of specific cardiac repolarization conditions.

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Title:Cardiac Repolarization: Bridging Basic and Clinical ScienceFormat:PaperbackDimensions:565 pages, 10 × 7.01 × 0.04 inPublished:November 9, 2010Publisher:Humana PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:1617373362

ISBN - 13:9781617373367

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Table of Contents

Part I. IntroductionChapter 1. Ventricular Repolarization and the Identification of the Sudden Death Candidate: Hype or Hope?Hein J. Wellens and Douglas P. ZipesChapter 2. Historical Milestones of Electrical Signal Recording and AnalysisThorsten Lewalter and Berndt LuderitzPart II. Basic Electrophysiology, Pharmacology, and Molecular Biology of Ventricular RepolarizationEdited by Charles AntzelevitchChapter 3. Physiology and Molecular Biology of Ion Channels Contributing to Ventricular RepolarizationJeanne M. Nerbonne and Robert S. KassChapter 4. Electrophysiology and Pharmacology of Ventricular RepolarizationCharles Antzelevitch, Andrew C. Zygmunt, and Robert DumaineChapter 5. How Do We Measure Repolarization inside the Heart?Charles Antzelevitch, Andrew C. Zygmunt, Jeffrey Fish, Guillermo Perez, and Fabiana ScornikChapter 6. Contribution of Electrical Heterogeneity of Repolarization to the ECGCharles Antzelevitch and Vladislav V. NesterenkoChapter 7. Electrical and Structural Remodeling of the Ventricular Myocardium in DiseaseAntonis A. Armoundas and Gordon F. TomaselliChapter 8. Ischemia-Related Changes in RepolarizationAndré G. Kléber and Michiel J. JanseChapter 9. The Long QT Syndrome: Molecular and Genetic AspectsCarlo Napolitano and Silvia G. PrioriChapter 10. Ion Channel Disease as a Cause of the Brugada Syndrome: Molecular and Genetic AspectsConnie R. Bezzina and Arthur A. M. WildeChapter 11. Cellular and Ionic Mechanisms Underlying ArrhythmogenesisCharles Antzelevitch, Alexander Burashnikov, and Jose Di DiegoPart III. Clinical Physiology and Pathophysiology of Ventricular Repolarization: Theory and PracticeEdited by Steven C. Hammill, Win K-Kuang Shen, and Ihor GussakChapter 12. Evaluation of Ventricular Repolarization: The Clinician's PerspectiveJan Nemec, Steven C. Hammill, and Win-Kuang ShenChapter 13. Human Cardiac RepolarizationPhilip T. SagerChapter 14. QT interval and Its Drug-Induced ProlongationWojciech Zareba and Arthur J. MossChapter 15. Neuro-Mediated Repolarization AbnormalitiesPhilippe Coumel and Pierre Maison-BlancheChapter 16. The Electrophysiologic Matrix: Equilibrium and Arnsdorf's ParadoxMorton F. ArnsdorfChapter 17. Antiarrhythmic Drugs and Future DirectionArshad Jahangir, Andre Terzic, and Win-Kuan ShenPart IV. Specific Electrocardiographic Phenomena and Clinical Syndromes of Ventricular RepolarizationEdited by Ihor Gussak, Charles Antzelevitch, and Preben BjerregaardChapter 18. ECG Phenomena of the Early Ventricular Repolarization: Early Repolarization SyndromeIhor Gussak, Charles Antzelevitch, and Preben BjerregaardChapter 19. The Brugada SyndromePedro Brugada, Ramon Brugada, Charles Antzelevitch, Koonlawee Nademanee, Jeffrey Towbin, and Josep BrugadaChapter 20. Clinical Evaluation, Risk Stratification, and Management of Congenital Long QT SyndromeAnant Khositseth and Michael J. AckermanChapter 21. Prolonged Repolarization and Sudden Infant Death SyndromePeter J. SchwartzChapter 22. Short QT Interval: ECG Phenomenon and Clinical Syndrome, Ihor Gussak, Charles AntzelevitchDaniel Goodman, and Preben BjerregaardChapter 23. T-Wave Alterans: Mechanisms, Relevance, and Clinical ImplicationsEtienne Pruvot and David S. Rosenbaum. Index.

Editorial Reviews

"This comprehensive survey of the latest research and clinical findings in ventricular repolarization will certainly help to bridge the gap between basic and clinical science." - Acta Cardiologica