Cardiovascular Pharmacogenetics by Martin R. WilkinsCardiovascular Pharmacogenetics by Martin R. Wilkins

Cardiovascular Pharmacogenetics

EditorMartin R. Wilkins

Hardcover | December 2, 2003

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This volume intends to provide a panorama of our current understanding of the role of genetic information in the management of cardiovascular disease. A recurring plea from the contributors is the need for more hypothesis-driven, rigorously conducted and analysed clinical research. Perhaps this compilation of knowledge will provide a springboard for the design of informative clinical studies.
Title:Cardiovascular PharmacogeneticsFormat:HardcoverDimensions:417 pagesPublished:December 2, 2003Publisher:Springer Berlin HeidelbergLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:3540402047

ISBN - 13:9783540402046

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Table of Contents

Preface.- The Role of Genotyping in Pharmacological Therapy.- Pharmacogenetics and the Treatment of Cardiovascular Disease.- Genetic Polymorphisms and Cardiovascular Drug Metabolism.- Genes that Modify Susceptibility to Atherosclerosis: Targets for Drug Action.- Lipid  Lowering Responses Modified by Genetic Variation.- The Genetic Basis of Essential Hypertension and its Implications for Treatment.- Genetics Predisposition to Cardiac Hypertrophy.- Genetic Determinants of Susceptibility, Prognosis and Treatment in Heart Failure.- The Genetics of Cardiac Channelopathies: Implications for Therapeutics.- Insulin Resistance and Cardiovascular Disease - New Insights From Genetics.- Genetic Disruption of Nitric Oxide Synthases and Cardiovascular Disease - Lessons from a Candidate Gene.- Association of Thrombotic Disease with Genetic Polymorphism of Haemostatic Genes - Relevance to Pharmacogenetics.- Genetic Polymorphisms of Adhesion Molecules.- Genetic Regulation of Metalloproteinase Activity: Pathogenic and Therapeutic Implications.- Current Perspectives on Gene and Cell-based Therapies for Myocardial Protection, Rescue and Repair.