Care of the Jaundiced Neonate

Hardcover | July 4, 2012

byDavid Stevenson, M. Jeffrey Maisels, Jon Watchko

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A complete, authoritative guide to the management and treatment of neonatal jaundice

Care of the Jaundiced Neonate focuses exclusively on the scientific underpinnings of jaundice, as well as the care of the jaundiced neonate. Edited by three of the field’s most respected neonatal care experts, the book uniquely explains how the imbalance between bilirubin production and elimination leads to jaundice—and that hazardous levels of unconjugated bilirubin can cause kernicterus, or brain damage. In addition, you’ll find the most current and clinically relevant perspectives on the physiology, genetics, and treatment of neonatal jaundice and related hemolytic conditions.

FEATURES

  • Covers all aspects of neonatal jaundice—from the biochemistry of bilirubin production to kernicterus
  • Begins with an in-depth examination of the complex gene-environment interactions of bilirubin-induced neurotoxicity and its role in neonatal jaundice
  • Surveys bilirubin production and measurement, its various fractions, and the metabolism and transport of bilirubin
  • Selected chapters highlight the physiology and epidemiology of neonatal unconjugated hyperbilirubinemia; bilirubin toxicity; prevention, screening, and postnatal management; phototherapy and other treatments; and prevention-related public policy.
  • Concluding chapter provides an overview of the key issues surrounding the incidence of neonatal jaundice in low-middle income countries
  • Includes informative review of risk assessment and treatment with phototherapy and other modalities provide key approaches to the effective clinical management of neonatal hyperbilirubinemia

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From the Publisher

A complete, authoritative guide to the management and treatment of neonatal jaundiceCare of the Jaundiced Neonate focuses exclusively on the scientific underpinnings of jaundice, as well as the care of the jaundiced neonate. Edited by three of the field’s most respected neonatal care experts, the book uniquely explains how the imbalanc...

David K. Stevenson is Harold K. Faber Professor of Pediatrics, Professor of Ob-Gyn, Senior Associate Dean for Academic Affairs, and Vice Dean, Stanford University School of Medicine, Palo Alto, CA; and Director, Charles B. and Ann L. Johnson Center for Pregnancy and Newborn Services, Lucile Packard Children's Hospital at Stanford. ...

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Format:HardcoverDimensions:9.6 × 7.5 × 0.7 inPublished:July 4, 2012Publisher:McGraw-Hill EducationLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0071762892

ISBN - 13:9780071762892

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Table of Contents

Chapter 1. Genetics of Neonatal Jaundice
Chapter 2. Bilirubin Production and Its Measurement
Chapter 3. Bilirubin and Its Various Fractions
Chapter 4. Bilirubin Metabolism and Transport
Chapter 5. Physiology of Neonatal Unconjugated Hyperbilirubinemia
Chapter 6. The Epidemiology of Neonatal Hyperbilirubinemia
Chapter 7. Bilirubin Toxicity
Chapter 8. Hemolytic Disorders and Their Management
Chapter 9. Prevention, Screening and Postnatal Management of Neonatal Hyperbilirubinemia
Chapter 10. Phototherapy and Other Treatments
Chapter 11. Kernicterus
Chapter 12. Public Policy to Prevent Severe Neonatal Hyperbilirubinemia
Chapter 13. Neonatal Jaundice in Low-Middle-Income Countries

Editorial Reviews

5 Stars! 100/100 Perfect ScoreReviewer Jay Goldsmith, MD (Tulane University School of Medicine) Description This relatively small book (285 pages) pulls together all of the recent advances in the science of bilirubin and the prevention of bilirubin encephalopathy in neonates. Edited by three of the foremost authorities on this topic and written by 24 worldwide experts, the book presents in very readable fashion the most up-to-date science and clinical aspects of neonatal jaundice. Purpose It is intended for both clinicians and investigators as a basis for present day treatment and a stimulus for further investigation. While jaundice is perhaps the most common symptom in neonates, the syndrome of bilirubin neurotoxicity is relatively rare, affecting 1:50,000 to 1 in 200,000 newborns each year. Recent guidelines and reviews as well as alerts from healthcare organizations have focused attention on this problem as potentially preventable. However, not since 1980, when Dr. O'Dell published a book on neonatal hyperbilirubinemia, has this type of comprehensive review been available. The authors have certainly met their objectives in creating this essential reference.Audience The audience includes any healthcare providers who treat newborns or who are interested in the science of bilirubin. The writing is clear and concise and the illustrations and tables, many in color, are easy to understand and complement the text. The editors are internationally known experts in this field and the international group of contributors have similar qualifications.Features The 13 chapters review the science of bilirubin (genetics, biochemistry, transport, and metabolism) and then the clinical aspects of jaundice management including epidemiology, public policy, phototherapy, and other treatments. An excellent review of the biochemistry of bilirubin toxicity is complemented by a full chapter on kernicterus. The easy-to-read text is complemented by some wonderful color drawings and photomicrographs. I could find no serious omissions from this comprehensive review. Assessment Although every general neonatal textbook has a chapter on hyperbilirubinemia and there have been several comprehensive reviews in major journals over the last decade, there has not been a complete review of this type for over 30 years. This book is strongly recommended to all healthcare providers who care for neonates.Reviewer Jay Goldsmith, MD (Tulane University School of Medicine) Range Question Score 1-10 Are the author's objectives met? 10 1-10 Rate the worthiness of those objectives. 10 1-5 Is this written at an appropriate level? 5 1-5 Is there significant duplication? (1=significant, 5=insignificant) 5 1-5 Are there significant omissions? (1=significant, 5=insignificant) 5 1-5 Rate the authority of the authors. 5 1-5 Are there sufficient illustrations? 5 1-5 Rate the pedagogic value of the illustrations. 5 1-5 Rate the print quality of the illustrations. 5 1-5 Are there sufficient references? 5 1-5 Rate the currency of the references. 5 1-5 Rate the pertinence of the references. 5 1-5 Rate the helpfulness of the index. 5 1-5 If important in this specialty, rate the physical appearance of the book 5 1-10 Is this a worthwhile contribution to the field? 10 1-10 If this is a 2nd or later edition, is this new edition needed? N/A