Cell Polarity In Development And Disease by Douglas W HoustonCell Polarity In Development And Disease by Douglas W Houston

Cell Polarity In Development And Disease

byDouglas W Houston

Paperback | November 2, 2017

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Cell Polarity in Development and Diseaseoffers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss and gain of cell polarity in the onset and progression of cancer. This book provides a basic resource for understanding the biology of polarity, offering a starting point for those thinking of targeting cell polarity for translational medical research.



  • Provides basic science understanding of cell polarity disease and development
  • Covers diseases affecting polarized epithelial tissues in the lung and kidney, also covering the progression of cancer
  • Includes historical context of cell polarity research for potential future breakthroughs
Douglas Houston is a Professor at the University of Iowa. His research is focused on a central problem in developmental biology: how a single-celled egg differentiates into an organism containing many different cell and tissue types. Using frog embryos as a model organism, he and his lab have isolated numerous novel genes with potentia...
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Title:Cell Polarity In Development And DiseaseFormat:PaperbackDimensions:236 pages, 8.75 × 6.35 × 0.68 inPublished:November 2, 2017Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0128024380

ISBN - 13:9780128024386

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Table of Contents

1. Overview of cell polarity: insights from model organisms and cellular systems
2. Cell polarity in the egg and early embyro- mammal
3. Pluripotency and cell polarity
4. The role of cell polarity in adult stem cell maintenance
5. Integration of cell polarity and growth factor signaling
6. Cell polarity and the onset and progression of cancer
7. Cell division and cell polarity
8. Polarized membrane/vesicle trafficking and disease
9. Polarized microtubule transport and disease
10. Regulation of cell polarity in cell/neuronal migration
11. Apical and planar cell polarity in ciliated epithelia
12. Renal epithelial cell polarity and disease
13. Hepatic cell polarity and disease
14. Epidermal cell polarity and disease
15. Cell polarity and sensory cell defects