Cell Signalling by John T. HancockCell Signalling by John T. Hancock

Cell Signalling

byJohn T. Hancock

Paperback | January 9, 2017

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Signalling within and between cells is one of the most important aspects of modern biochemistry and cell biology. An understanding of signalling pathways is vital to a wide range of biologists, from those who are investigating the causes of cancer, to those who are concerned about the impactof environmental pollutants on the ecosystem. The way cells adapt to changing environments, and the way cell dysfunction causes disease, is underpinned by cell signalling events. Cell Signalling presents a carefully structured and highly accessible introduction to this intricate and rapidly growing field. Starting with an overview of cell signalling and highlighting its importance in many biological systems, the book goes on to explore the key components of extracellular andintracellular signalling mechanisms, before examining how these components come together to create signalling pathways. A focus on common components and concepts, rather than mechanistic detail, allows the reader to gain a thorough understanding of the principles that underpin cell signalling. Online Resource CentreThe Online Resource Centre to accompany Cell Signalling features:For students:* Links to useful websitesFor registered adopters of the text:* Journal Clubs: suggested research papers and discussion questions linked to topics featured in the book* Figures from the book in electronic format for use in lectures
John Hancock is Professor of Cell Signalling at the University of the West of England. He has had a long standing interest in cell signalling and redox biology, and tries to bring these together as much as possible in his research. In addition to Cell Signalling he has published several reviews on nitric oxide and reactive oxygen speci...
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Title:Cell SignallingFormat:PaperbackDimensions:456 pages, 9.69 × 7.44 × 0.03 inPublished:January 9, 2017Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:019965848X

ISBN - 13:9780199658480

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Table of Contents

Part 1: An overview of signalling1. Aspects of cellular signalling2. Pathways are the key to signalling3. A look at some of the history and techniques of cell signallingPart 2: Components that comprise signalling pathways4. Extracellular signals: hormones, cytokines and growth factors5. Detection of extracellular signals: the role of receptors6. Protein phosphorylation, kinases and phosphatases7. Cyclic nucleotides, cyclases and G proteins8. Inositol phosphate metabolism and roles of membrane lipids9. Intracellular calcium ions: control of their concentrations and roles in signalling10. Reactive oxygen species, reactive nitrogen species and redox signallingPart 3: Selected examples of signalling pathways and events11. Insulin and the signal transduction cascades it invokes12. Perception of the environment13. Signalling in development and for the regulation of gene expression14. Life, death and apoptosisPart 4: Final thoughts15. Cell signalling: importance, complexity and the future

Editorial Reviews

Review from previous edition: "Complexity and specificity are the hallmarks of cell signalling, yet Hancock in this third edition has gone a long way to simplify these complicated processes. His signalling examples are clever and well-conceived, his writing descriptive and his passion for hissubject infectious ... this is marvellous value for money and is a worthy companion to an undergraduate/postgraduate reference library." --John P. Phelan, Waterford Institute of Technology, Ireland in The Biochemist