Cellular And Molecular Neurophysiology

Hardcover | January 6, 2015

byConstance HammondEditorConstance Hammond

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This new, thoroughly revised fourth edition is the only current, established and authoritative text focusing on the cellular and molecular physiology of nerve cells. Understanding the functioning of the neuron, the basic cell of the central nervous system requires a clear understanding of the cellular and molecular physiology of the neuron. The book is hypothesis driven rather than just presenting the facts, and the content is firmly based on numerous experiments performed by the top experts in the field. While the book does cover the important facts, it also presents the background for how researchers arrived at this knowledge to provide a context for the field. It teaches not only how excitable cells work in detail, but also how to construct and conduct intelligent research experiments. This book promotes a real understanding of the function of nerve cells that is useful for practicing neurophysiologists and students in a graduate-level course on the topic alike. 70% new or updated material in full color throughout, with more than 350 carefully selected and constructed illustrations Fifteen appendices describing neurobiological techniques are interspersed in the text Accompanying Instructor website with exercises and Companion website available

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From the Publisher

This new, thoroughly revised fourth edition is the only current, established and authoritative text focusing on the cellular and molecular physiology of nerve cells. Understanding the functioning of the neuron, the basic cell of the central nervous system requires a clear understanding of the cellular and molecular physiology of the ne...

From the Jacket

This new, thoroughly revised fourth edition is the only current, established and authoritative text focusing on the cellular and molecular physiology of nerve cells. Understanding the functioning of the neuron, the basic cell of the central nervous system requires a clear understanding of the cellular and molecular physiology of the ne...

Constance Hammond is an INSERM director of research at the Mediterranean Institute of Neurobiology. A renowned Parkinson's disease investigator, in 2012 she became a Chevalier of the Légion d'Honneur in recognition for her services to scientific communication. Studying biology at the University of Pierre and Marie Curie and the Ecole N...

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Format:HardcoverDimensions:444 pages, 9.41 × 7.24 × 0.98 inPublished:January 6, 2015Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0123970326

ISBN - 13:9780123970329

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Table of Contents

Part I. Neurons: Excitable and Secretory Cells That Establish Synapses 1. Neurons 2. Neuron Glial Cell Cooperation 3. Ionic Gradients, Membrane Potential and Ionic Currents 4. The Voltage-Gated Channels of Na+ Action Potentials 5. The Voltage-Gated Channels of Ca+2 Action Potentials: Generalization 6. The Chemical Synapses 7. Neurotransmitter ReleasePart II. Ionotropic and Metabotropic Receptors in Synaptic Transmission and Sensory Transduction 8. The Ionotropic Nicotinic Acetycholine Receptors 9. The Ionotropic GABAA Receptor 10. The Ionotropic Glutamate Receptors 11. The Metabotropic GABAB Receptors 12. The Metabotropic Glutamate ReceptorsPart III. Somato-Dendritic Processing and Plasticity of Postsynaptic Potentials 13. Somato-Dendritic Processing of Postsynaptic Potentials I: Passive Properties of Dendrites 14. Subliminal Voltage-Gated Currents of the Somato-Dendritic Membrane 15. Somato-Dendritic Processing of Postsynaptic Potentials II: Role of Subthreshold Depolarizing Voltage-Gated Currents 16. Somato-Dendritic Processing of Postsynaptic Potentials III: Role of High Voltage-Activated Depolarizing Currents 17. Firing Patterns of Neurons 18. Synaptic PlasticityPart IV. The Adult Hippocampal Network 19. The Adult Hippocampal Network 20. Maturation of the Hippocampal Network

Editorial Reviews

"In its third internationally acclaimed edition, this textbook provides an unrivaled account of the basic foundations of molecular and cellular neurophysiology. For those of us who were inclined to believe that the unprecedented development of neuroscience made neurophysiology disposable, Constance Hammond proves us with conviction and elegance that this is just not the case!"-Dr. Robert Dantzer, Professor of Psychoneuroimmunology, Integrative Immunology and Behavior Program University of Illinois at Urbana-Champaign"...a very fluid and self consistent read which should be of interest to neophytes and advanced students alike."-Jean-Marc Fellous, Professor Psychology, Neuroscience, Cognitive Sciences, and Applied Mathematics, University of Arizona, Tucson"A particularly strong feature of the book is that most of the exposition is driven by data from original experiments, supplying many figures that offer a ready-made basis for lectures (figures are available on the instructor's website)." Jim Belanger, Department of Biology, West Virginia University"More than any similar volume that I have come across in recent years, this one has the potential of luring students of neuroscience and even students from other fields to build a career in neurophysiology."György Buzsáki, M.D., Ph.D., Board of Governors Professor, Center for Molecular and Behavioral Neuroscience, Rutgers University"...this book is a very precious and unique tool, ideal for students with a strong interest in neuroscience." --Jean-Francois Perrier, Institute of Neuroscience and Pharmacology, University of Copenhagen, Denmark"This is an outstanding book that I will definitely recommend to my students." --Peter Somogyi, Oxford University, United Kingdom