Channels, Carriers, And Pumps: An Introduction To Membrane Transport

Paperback | October 30, 2017

byWilfred D. Stein, Thomas Litman

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An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components channels, carriers, and pumps . The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered. Provides an introduction to the properties of transport proteins: channels, carriers, and pumps Presents up-to-date information on the structure of transport proteins and on their function and regulation Includes introductions to transport kinetics and to the cloning of genes that code transport proteins Furnishes a link between the experimental basis of the subject and theoretical model building

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An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components channels, carriers, and pumps . The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molec...

Wilfred Stein is the author of three previous books on membrane transport, the first appearing almost fifty years ago. He has edited numerous books and written some 180 papers on various aspects of membrane transport and especially transport kinetics. These papers, especially those written together with his colleague William Lieb, defi...

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Format:PaperbackDimensions:422 pages, 8.75 × 6.35 × 0.68 inPublished:October 30, 2017Publisher:Academic PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0128102926

ISBN - 13:9780128102923

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Table of Contents

Chapters Structural Basis of Movement Across Cell Membranes Simple Diffusion of Nonelectrolytes and Ions Ion Channels Across Cell Membranes Carrier-Mediated Transport: Facilitated Diffusion Coupling of Flows of Substrates: Antiporters and Symporters Primary Active Transport Systems The Regulation and Integration of Transport SystemsAppendices Single and Triple-Letter Codes for the Amino Acids Fundamental Constants, Conversion Factors, and Some Useful Approximations The Relation between the Permeability Coefficient Ps and the Half-Time t1/2 of Entry of a Permeant