Chemical Synthesis: Gnosis to Prognosis by C. ChatgilialogluChemical Synthesis: Gnosis to Prognosis by C. Chatgilialoglu

Chemical Synthesis: Gnosis to Prognosis

byC. ChatgilialogluEditorV. Snieckus

Paperback | November 15, 2011

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This volume demonstrates that chemical synthesis is fully undeserving of the label `mature science'. Although chemists are increasingly able to provide some solutions in the construction of natural and biologically active products, synthesis is facing formidable challenges in the emerging areas of bioorganic chemistry, molecular biology, materials science and polymer science. This unique book presents the lectures and discussions of an outstanding group of such interdisciplinary scientists. Unperturbed by excessive structure and time constraints, the group talked about the current status of their areas (gnosis) and mused on their future directions (prognosis). Individual lectures and panels led naturally to questions and discussion, expression of alternative points of view, and thought provoking suggestions. To the chemist who is increasingly aware of the breakdown of barriers in chemistry, biology and materials science, this book is a source of provocative thought and an arrow pointing to the central role of synthesis in the way chemistry impinges on scientific activity.
Title:Chemical Synthesis: Gnosis to PrognosisFormat:PaperbackDimensions:625 pages, 24 × 16 × 0.07 inPublished:November 15, 2011Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:9401065985

ISBN - 13:9789401065986

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Table of Contents

Preface. Asymmetric Synthesis: I - Fundamentals and Recent Advances. II - Some Aspects of Asymmetric Catalysis with Transition-Metal Complexes; H.B. Kagan. Addition of Enolates and Metalloalkyls to Imines. Stereospecific Synthesis of beta-Lactams, Amines, Aziridines and Aminols; G. Cainelli, et al. Target-Driven Organic Synthesis: Reflections on the Past, Prospects for the Future; S. Hanessian. Optically Active Transition Metal Compounds Containing Chiral Transition Metal Atoms; H. Brunner. Biomimetic Chemistry. Bifunctional Binding and Catalysis; R. Breslow. Design of Enzyme Inhibitors. Answering Biological Questions Through Organic Synthesis; P.A. Bartless. Enantioselective Catalysis with Transition Metal Complexes; H. Brunner. Directed Aromatic Metalation: A Continuing Education in Flatland Chemistry; V. Snieckus. Panel Discussion I. As We Head Into the 21st Century, is There Still Value in Total Synthesis of Natural Products as a Research Endeavor? C.H. Heathcock. Convergent Strategies for Synthetic Receptors; P. Timmerman, et al. The Advancement of Radical-Based Synthetic Strategies: From Reagent Design to Polymer Modification; C. Chatgilialoglu. Templated Synthesis of Enzyme Mimics: How Far Can We Go? S. Anderson, J.K.M. Sanders. Towards a Chemical Etiology of the Natural Nucleic Acids' Structure; A. Eschenmoser. Principles of Antibody Catalysis; D. Hilvert. New Homocalixarenes and Catenanes: From Molecular Recognition to Mechanical Bonds; S. Meier, et al. Self-Assembly in Chemical Synthesis; S.J. Langford, J.F. Stoddart. Oligonucleotide-Directed Recognition of Double-Helical DNA; C. Hélène, T. Garestier. Can Enzyme Mimics Compete With Catalytic Antibodies? C.J. Walter, et al. Panel Discussion II. Synthesis of Giant Modular Structures: Supramolecular Assemblies and Well-Defined Macro-Molecules; J. Michl. Polymer Synthesis and Stereochemistry with Transition Metal Catalysts; R. Waymouth, et al. Making Unnatural Products by Natural Means; S.J. Langford, J.F. Stoddart. Supramolecular Chemistry and Chemical Synthesis. From Molecular Interactions to Self-Assembly; J.-M. Lehn. Synthetic Approaches to Functional Polymers; F. Ciardelli, et al. Transduction of Molecular Interactions into Macroscopic Properties; H.C. Visser, et al. Approaches to Synthesis Based on Non-Covalent Bonds; G.M. Whitesides, et al. Panel Discussion III. Organic Synthesis and the Life Sciences; D. Arigoni. Index.