Chromatin Structure and Gene Expression

Paperback | November 1, 2000

EditorSarah Elgin, Jerry Workman

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Since publication of the first edition in 1995, there have been significant advances and understanding of chromatin structure and its relation to gene expression. These include a high-resolution structure of the nucleosome core, discovery of the enzymes and complexes that mediate histoneacetylation and deacetylation, discovery of novel ATP-dependent chromatin remodeling complexes, new insights into nuclear organization and epigenetic silencing mechanisms. In light of these advances, Chromatin Structure and Gene Expression (2ed.) includes updated chapters and additional materialthat introduce new concepts in the process of gene regulation in chromatin.

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From the Publisher

Since publication of the first edition in 1995, there have been significant advances and understanding of chromatin structure and its relation to gene expression. These include a high-resolution structure of the nucleosome core, discovery of the enzymes and complexes that mediate histoneacetylation and deacetylation, discovery of nove...

Sarah Elgin is at Washington University, St Louis. Jerry Workman is at Howard Hughes Medical Institute, Pennsylvania State University.
Format:PaperbackDimensions:354 pages, 9.69 × 7.44 × 0.79 inPublished:November 1, 2000Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:019963890X

ISBN - 13:9780199638901

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Table of Contents

Nucleosome and Chromatin StructureDNA Replication, Nucleotide Excision Repair and Nucleosome AssemblyChromatin Structure and Control of Transcription in VivoThe Genetics of Chromatin FunctionThe SWI/SNF family of remodeling complexesATP-Dependent Chromatin Remodeling and Assembly by the ISWI ComplexesHistone Acetyltransferase/Transcription Coactivator ComplexesHistone Deacetylation: mechanisms of repressionDevelopmental Regulation of Chromatin Function and Gene ExpressionChromatin Contributions to Epigenetic Transcriptional States in YeastEpigenetic Regulation in Drosophila: unraveling the conspiracy of silenceEpigenetics in MammalsChromatin BoundariesLinking Large-Scale Chromatin Structure with Nuclear Function