Cluster Headache and Related Conditions

Hardcover | November 18, 1999

EditorJes Olesen, Peter Goadsby

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Cluster headache affects 0.1% of the population and is a severe form of primary headache. This volume of Frontiers in Headache Research is the only up-to-date and comprehensive review of the condition and its related disorders. The book begins with a discussion of the basic circadian biologyof the condition followed by an overview of relevant epidemiological studies. Cluster headache is then described in comparison with related disorders, including paroxysmal hemicrania, SUNCT, hemicrania continua and hypnic headache, and the system of classification discussed. The volume then moveson to look at the wealth of basic research into cluster headache, including, animal studies, work on the autonomic nervous system in man, neuropeptide research, studies of biological rhythms, the associated endocrinology, information derived from neuroimaging and the influence of genetic factors.The final sections of the book examine acute treatment, prophylaxis, the potential for surgical treatment and the opportunities for further innovative therapies. The contributing authors are all international specialists in this field.

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Cluster headache affects 0.1% of the population and is a severe form of primary headache. This volume of Frontiers in Headache Research is the only up-to-date and comprehensive review of the condition and its related disorders. The book begins with a discussion of the basic circadian biologyof the condition followed by an overview of...

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Format:HardcoverPublished:November 18, 1999Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0192630733

ISBN - 13:9780192630735

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Table of Contents

Part I: Cluster Headache: The Clinical Picture 1. Molecular circadian biology 2. Cluster headache: a clinical and pathophysical overview 3. Epidemiology of cluster headache 4. Paroxysmal hemicrania 5. Case-control study on the epidemiology of cluster headache 6. Episodic and chronic cluster headache males: differences in age at onset and habits 7. Gender ratio in cluster headache 8. Cluster headache after iatrogenic lesions of the head 9. Cluster headache prevalence in a general population 10. Diagnostic patterns in cluster headache 11. Cluster headache - the clinical picture: Discussion summary Part II: Trigeminal-autonomic cephalgias 12. SUNCT syndrome: the clinical picture 13. Hemicrania continua and hypnic headache 14. International Headache Society classification of trigeminal autonomic cephalgias (TACs) 15. meta-Chlorophenylpiperazine as an agent for provoking cluster headache attacks: a study versus placebo 16. Seratonergic hypothalamic responses are altered in both phases of cluster headache: a neuroendocrinological study 17. Head pain in cluster headache patients does not correlate to abnormalities in nasal and sinusal structures 18. Trigeminal-autonomic cephalgias: Discussion summary Part III: Mechanisms of Cluster Headache and Related Conditions I 19. Animal studies relevant to cluster headache 20. The pathophysiology of autonomic disturbances in cluster headache 21. Neuropeptides in cluster headache, trigeminal neuralgia, and chronic paroxysmal hemicrania 22. Nitric oxide plasma concentrations in both phases of cluster headache 23. Nitric oxide synthase activation in cluster headache florid phase 24. Cluster headache: one syndrome, but more than one aetiological possibility 25. Ipsilateral impairment of somatosensory trigeminal evoked potentials but not of blink reflex in cluster headache 26. Autonomic nervous system function in cluster headache: pupillary and cardiovascular responses to cold pressor test 27. Mechanisms of cluster headache and related conditions I: Discussion summary Part IV: Mechanisms of Cluster Headache and Related Conditions II 28. Functional imaging of cluster headache: insights into an idiopathic headache syndrome 29. Biological rhythms in cluster headache 30. Endocrinology of cluster headache 31. Genetics of cluster headache 32. Is cluster headache associated with a systemic inflammation? 33. Sleep characteristics and psychological peculiarities in cluster headache subjects 34. Involvement of cognitive processing in cluster headache 35. Increased sensitivity to light and sound during cluster headache bout 36. Genetic heterogeneity in cluster headache 37. Mechanisms of cluster headache and related conditions II: Discussion summary Part V: Cluster Headache: General Management and Acute Treatment 38. General counselling 39. Treatment of cluster headache attacks with sumatriptan 40. Cluster headache: treatments other than sumatriptan in acute attacks 40a. Sumatriptan in the treatment of cluster headache 41. Effects of octreotide, a somatostatin analogue, on severe cluster-headache-like hemicrania after pituitary operation: implications for the pathogenesis of chronic cluster headache 42. Cluster headache: general management and acute treatment: Discussion summary Part VI: Cluster Headache: Prophylaxis And The Future 43. Prophylactic pharmacotherapy of cluster headache 44. Surgical and ablative management of cluster headache 45. Future treatments for cluster headache 46. RS-127445, a selective 5-HT2B receptor antagonist, blocks mCPP-evoked plasma protein extravasation in dura mater and capsaicin-evoked c-fos expression in trigeminal nucleus caudalis of rat 47. 'Continuous' cluster-like headache with response to sumatriptan and steroids 48. Trigeminal nerve section for chronic migrainous neuralgia 49. Verapamil is an effective prophylactic for cluster headache: results of a double-blind multicentre study versus placebo 50. Cluster headache: prophylactics and the future: Discussion summary