Cognition in Schizophrenia: Impairments, Importance and Treatment Strategies

Paperback | September 1, 2000

EditorTonmoy Sharma, Philip Harvey

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Although it has been known for 100 years that cognitive functioning is impaired in schizophrenia, the implications of this impairment have only recently been clearly understood. While in the past, cognitive deficits were thought to be the result of other aspects of the illness, such as poorco- operation, or as a result of the treatment of the illness, it is now known that these factors exert only a very minor influence on cognitive deficit. This book, with contributions from the major international names in the field, reviews the most recent research on the impairment of cognitivefunctioning in schizophrenia, covering: what it is, how wide-ranging it can be, what the clinical implications are, and how it can be treated? The book is divided into three sections. The first section provides background information on the important aspects of cognitive functioning inschizophrenia. The second section provides information on the correlates of cognitive functioning, examining classical symptoms of the illness, as well as social and adaptive functional deficits. The final section provides information on the treatment of cognitive functioning in schizophrenia,from the older less effective treatments with conventional antipsychotics, to the developing treatment strategies using experimental compounds. A clear insight into cognitive deficit is the key to understanding why previous treatments have failed, and the key by which new treatments may change thisterrible illness, treatments significantly more effective than earlier interventions.

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Although it has been known for 100 years that cognitive functioning is impaired in schizophrenia, the implications of this impairment have only recently been clearly understood. While in the past, cognitive deficits were thought to be the result of other aspects of the illness, such as poorco- operation, or as a result of the treatmen...

Philip D Harvey PhD Department of Psychiatry Box 1229 Mt Sinai School of Medicine New York NY 10029 USA Tel: 001 212 824 7140 Fax: 001 212 869 3945 Email: pdharvey@compuserve.com Dr Tonmoy Sharma Section of Cognitive Psychopharmacology Institute of Psychiatry De Crespigny Park Denmark Hill London SE5 8AF Tel: +44 171 919 2678 Fax:...

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Format:PaperbackPublished:September 1, 2000Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:019262993X

ISBN - 13:9780192629937

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Table of Contents

Section One: The Impairments of Cognitive Functioning in Schizophrenia1. The Course of Cognitve Impairment in Patients with Schizophrenia2. Working Memory Dysfunction and its Relevance to Schizophrenia3. Executive Dysfunction in Schizophrenia4. Learning and Memory in Schizophrenia5. Information Processing and Attention in Schizophrenia:clinical and functional correlates and treatment of cognitives impairment6. Formal Thought Disorder in Schizophrenia: characteristics and cognitive underpinnings7. Glutamatergic Contributions to Cognitive Dysfunction in SchizophreniaSection Two: The Importance of Cognitive Impairment and its Correlates in Schizophrenia8. Cognitive Functioning, Social Adjustment and Long-term Outcome in Schizophrenia9. Relevance of Neurocognitive Deficits for Functional Outcome in Schizophrenia10. Cognitive Functioning and Negative Symptoms in Schizophrenia11. Cognitive Impairments as Causes of Positive Symptoms in Schizophrenia12. Cognitive Functioning in Schizophrenic Patients with Comorbid Substance Use DisordersSection Three: Treatment For Cognitive Impairments13. Cognitive Effects of Typical Antipsychotic Treatment: anither look14. The Central Cholinergic System and Cognitive Dysfunction in Schizophrenia15. Cognitive Enhancement as a Treatment Strategy in Schizophrenia16. Specific Cognitive Enhancers17. Cognitive Rehabilitation and Remediation in SchizophreniaConclusions