Cognitive Impairment and Dementia in Parkinsons Disease

Hardcover | January 30, 2010

EditorMurat Emre

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Parkinson's disease has long been perceived as a pure motor disorder, partly due to its initial description by James Parkinson, who suggested that "senses and intellect remain intact", and partly due to the fact that patients with PD did not survive long, before effective treatment becameavailable. As the survival time of patients with Parkinson's disease has substantially increased due to modern treatment, it has become apparent that cognitive deficits and dementia are also frequent features, especially in elderly patients. With the progression of the disease and age, dementiadevelops in a substantial number of patients and constitutes a major therapeutic challenge. Dementia has thus increasingly been the focus of research and practice in recent years and a large body of knowledge has been accumulated. Despite these developments there has been no single volume dedicatedto this topic.This book provides an extensive overview of the current status of knowledge pertaining to cognitive impairment and dementia associated with Parkinson's disease, intended as a reference book for general neurologists, neurology residents and also those with a special interest in movement disorders. Inthis edited volume experts in the field describe in detail all aspects of cognitive impairment and dementia in Parkinson's disease, including epidemiology, spectrum of clinical features, pathology, neurochemistry and genetics, findings in auxiliary investigations, relation to other neurodegenerativedisorders, diagnostic process and management, and rounded up by discussion of future research directions and expectations. The text is complemented and enriched with tables, figures and heavily referenced to encompass all relevant literature.

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Parkinson's disease has long been perceived as a pure motor disorder, partly due to its initial description by James Parkinson, who suggested that "senses and intellect remain intact", and partly due to the fact that patients with PD did not survive long, before effective treatment becameavailable. As the survival time of patients with...

Professor Murat Emre was born in 1956 in Eregli, Turkey. After studying medicine at the Istanbul Faculty of Medicine he trained in Neuroscience and Clinical Neurology at the University of Zurich. He then worked in the fields of neurorehabilitation and clinical research in Switzerland for several years. He trained in movement disorders...

other books by Murat Emre

Format:HardcoverDimensions:288 pages, 9.69 × 6.73 × 0.8 inPublished:January 30, 2010Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199564116

ISBN - 13:9780199564118

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Table of Contents

1. Murat Emre: Introduction2. Dag Aarsland: The epidemiology of dementia associated with Parkinson's disease3. Murat Emre: General features, mode of onset and the course of dementia in Parkinson`s disease4. Kolbjorn Bronnick: Cognitive profile in Parkinson's disease dementia5. Daniel Weintraub and Eugenia Mamikonyan: Neuropsychiatric symptoms in Parkinson's disease dementia6. Paolo Barone and Gabriella Santangelo: The interaction between affect and executive functions in Parkinson's disease7. David J Burn: Motor symptoms and phenotype in patients with Parkinson's disease dementia8. JM Hausdorff, G Yogev-Seligman, M Plotnik, A Mirelman, N Giladi: Interaction between cognition and gait in patients with Parkinson's disease9. Eduardo Tolosa and Alex Iranzo: Disorders of sleep and autonomic function in Parkinson's disease dementia10. Michael J. Firbank and John T O'Brien: Neuroimaging11. Yasuyuki Okuma and Yoshikuni Mizuno: Electrophysiological and other auxiliary investigations in patients with Parkinson's disease dementia12. Rita Guerreiro, Andrew Singleton: The genetic basis of dementia in Parkinson's disease13. Margaret Ann Piggott and Elaine K Perry: Neurochemical pathology of Parkinson's disease dementia14. Gonzalo J. Revuelta and Carol Lippa: Pathological correlates of dementia in Parkinson's disease15. Elise Caccappolo and Karen Marder: Cognitive impairment in non-demented patients with Parkinson's disease16. Clive Ballard, Dag Aarsland: Spectrum of lewy body dementias: relationship of PD-D to DLB17. Jaime Kulisevsky and Javier Pagonabarraga: Spectrum of disorders with Parkinsonism and dementia18. Murat Emre: Diagnosis of dementia in Parkinson's disease19. Ian McKeith and Murat Emre: Management of Parkinson's disease dementia and dementia with lewy bodies20. John Hardy: Parkinson's disease: what will the future bring?