Cologne Atherosclerosis Conference No. 2: Lipids: 2nd Cologne Atherosclerosis Conference, Cologne, May 2-4, 1984 by ParnhamCologne Atherosclerosis Conference No. 2: Lipids: 2nd Cologne Atherosclerosis Conference, Cologne, May 2-4, 1984 by Parnham

Cologne Atherosclerosis Conference No. 2: Lipids: 2nd Cologne Atherosclerosis Conference, Cologne…

byParnham

Paperback | March 8, 2012

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This book contains the proceedings of the 2nd Cologne Ath<_rosclec2ad_20_rosis20_conference20_28_cac29_20_which20_was20_devoted20_to20_lipids2c_20_in20_particular20_lipoproteins.20_the20_object20_of20_the20_conference20_series2c_20_organised20_by20_a.20_nattermann20_26_20_cie.20_gmbh2c_20_cologne2c_20_is20_to20_provide20_an20_overview20_of20_various20_fields20_either20_directly20_related20_to20_or20_associated20_with20_the20_process20_of20_atherosclerosis.20_having20_considered20_the20_associated20_field20_of20_inflammation20_in20_the20_first20_conference2c_20_the20_2nd20_cac20_dealt20_with20_a20_subject20_intimately20_related20_to20_the20_atherosclerotic20_process20_per20_see20_the20_recent20_demonstration20_in20_an20_extensive20_clinical20_study20_of20_a20_close20_link20_between20_high20_plasma20_cholesterol20_and20_coronary20_mortality20_has20_awakened20_both20_the20_medical20_and20_the20_lay20_communities20_to20_the20_importance20_of20_research20_into20_lipoprotein20_biochemistry20_and20_physiology.20_this20_can20_only20_be20_good20_news20_since20_more20_intensive20_research20_into20_lipoprotein20_functions20_is20_vital20_for20_future20_therapy20_of20_atherosclerosis20_and20_other20_lipid20_disorders.20_the20_status20_of20_research20_on20_lipoproteins20_is20_reflected20_in20_the20_contributions20_to20_this20_book2c_20_which20_are20_of20_an20_interdisciplinary20_nature2c_20_including20_both20_reviews20_and20_shorter20_research20_reports20_by20_acknowledged20_experts20_in20_the20_field.20_special20_thanks20_are20_due20_to20_margret20_leffin20_for20_her20_organisational20_and20_secretarial20_assistance20_at20_all20_stages20_and20_to20_dr.20_d.20_bowyer20_and20_prof.20_w.20_stoffel20_for20_their20_advice20_and20_assistc2ad_20_ance20_with20_the20_programme.20_cologne2c_20_july20_198420_michael20_j20_e280a2_.20_parnham20_lipoprotein20_synthesis20_and20_receptor20_interactions20_1720_aas20_163a_20_2nd20_cologne20_atherosclerosis20_conference20_198420_c2a9_20_198420_birkhiiuser20_verlag20_basel20_apolipoprotein20_genes2c_20_dna20_polymorphisms20_and20_hyperlipidemia20_c.20_c.20_shoulders20_and20_f.20_e. rosis="" conference="" _28_cac29_="" which="" was="" devoted="" to="" _lipids2c_="" in="" particular="" lipoproteins.="" the="" object="" of="" _series2c_="" organised="" by="" a.="" nattermann="" _26_="" cie.="" _gmbh2c_="" _cologne2c_="" is="" provide="" an="" overview="" various="" fields="" either="" directly="" related="" or="" associated="" with="" process="" atherosclerosis.="" having="" considered="" field="" inflammation="" first="" _conference2c_="" 2nd="" cac="" dealt="" a="" subject="" intimately="" atherosclerotic="" per="" see="" recent="" demonstration="" extensive="" clinical="" study="" close="" link="" between="" high="" plasma="" cholesterol="" and="" coronary="" mortality="" has="" awakened="" both="" medical="" lay="" communities="" importance="" research="" into="" lipoprotein="" biochemistry="" physiology.="" this="" can="" only="" be="" good="" news="" since="" more="" intensive="" functions="" vital="" for="" future="" therapy="" atherosclerosis="" other="" lipid="" disorders.="" status="" on="" lipoproteins="" reflected="" contributions="" _book2c_="" are="" interdisciplinary="" _nature2c_="" including="" reviews="" shorter="" reports="" acknowledged="" experts="" field.="" special="" thanks="" due="" margret="" leffin="" her="" organisational="" secretarial="" assistance="" at="" all="" stages="" dr.="" d.="" bowyer="" prof.="" w.="" stoffel="" their="" advice="" _assistc2ad_="" ance="" programme.="" july="" 1984="" michael="" j="" _e280a2_.="" parnham="" synthesis="" receptor="" interactions="" 17="" aas="" _163a_="" cologne="" _c2a9_="" birkhiiuser="" verlag="" basel="" apolipoprotein="" _genes2c_="" dna="" polymorphisms="" hyperlipidemia="" c.="" shoulders="" f.="">
Title:Cologne Atherosclerosis Conference No. 2: Lipids: 2nd Cologne Atherosclerosis Conference, Cologne…Format:PaperbackDimensions:242 pages, 24.4 × 17 × 0.02 inPublished:March 8, 2012Publisher:Springer-Verlag/Sci-Tech/TradeLanguage:English

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ISBN - 10:3034872372

ISBN - 13:9783034872379

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Table of Contents

Lipoprotein Synthesis and Receptor Interactions.- Apolipoprotein genes, DNA polymorphisms and hyperlipidaemia.- The use of recombinant DNA technology to study polygenic hyperlipidaemia.- Lipoprotein synthesis (Abstract only).- The LDL receptor in lipoprotein turnover (Abstract only).- Receptor interactions controlling lipoprotein metabolism (Abstract only).- A saturable binding site for high density lipoprotein3 on human liver membranes.- Lipoprotein Metabolism.- Lipoprotein lipase - the molecule and its interactions.- Organ specific metabolism of low density lipoprotein and high density lipoprotein.- Metabolism of rat serum high-density lipoprotein apolipoprotein A-IV.- Importance of particle size and lipid composition in the transfer of plasma apolipoproteins to microemulsions.- The role of lysophosphatidylcholine in the regulation of the catabolism of triglyceriderich lipoproteins.- Hypercholesterolemic and diabetic serum decrease LDL-degradation by cathepsin D from human arterial smooth muscle cells and fibroblasts.- Metabolic channelling of apolipoprotein B in very low density lipoprotein.- Turnover of APOB in low density lipoprotein sub-fractions.- Lipoproteins and Macrophages.- Degradation of normal and abnormal plasma lipoproteins by cultured macrophages.- The role of macrophages in atherosclerosis (Abstract only).- The role of the monocyte/macrophage system in lipoprotein metabolism.- Solubilization and purification of an acetyl-LDL binding membrane protein from human leukocytes.- The effect of LDL and modified LDL on macrophage secretion products.- Macrophages, oxidised lipids and atherosclerosis.- Clinical Aspects.- Regulation of low density lipoprotein uptake and degradation in different animal species.- Regulation of LDL receptors in vivo.- Familial hypercholesterolemia proven by tissue culture and atherosclerosis in relation to other risk factors.- Familial hypertriglyceridemia and the regulation of lipid synthesis by insulin and triiodothyronine in human cell cultures.- Mutations of apolipoprotein AI can affect cofactor function for cholesteryl ester formation by lecithin: cholesterol acyltransferase.- Oral administration of polyunsaturated phosphatidylcholine reduces lipid and cholesterol contents in platelets of healthy volunteers.- Influence of age, body-weight, smoking habits and alcohol consumption on the lipoprotein profile: preliminary results from a study performed on 6543 male industrial workers aged 40-59 years.