Combinatorial Chemistry: A Practical Approach

Paperback | July 1, 2000

EditorHicham Fenniri

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Combinatorial Chemistry is a genuine practical guide covering all the major areas of combinatorial chemistry from an experimental and conceptual point of view. Being one of the most powerful of modern technologies, combinatorial chemistry has had implications to many areas of chemistry andbiology and the current approaches to drug, catalyst, receptor, and materials development and discovery are all included in this volume. It also contains protocols on solid, liquid, and solution phase synthesis and expedient methods of library screening and evaluation. The use of automation androbotics is also explained. It is written at a level easily accessible to novices and will enable readers to use combinatorial techniques to the best advantage.

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From the Publisher

Combinatorial Chemistry is a genuine practical guide covering all the major areas of combinatorial chemistry from an experimental and conceptual point of view. Being one of the most powerful of modern technologies, combinatorial chemistry has had implications to many areas of chemistry andbiology and the current approaches to drug, ca...

Hicham Fenniri is at Purdue University.
Format:PaperbackPublished:July 1, 2000Publisher:Oxford University PressLanguage:English

The following ISBNs are associated with this title:

ISBN - 10:0199637547

ISBN - 13:9780199637546

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Table of Contents

Synthesis of combinatorial libraries using the portioning-mixing procedureOne-bead-one-compound combinatorial library methodSynthesis and screening of positional scanning synthetic combinatorial librariesHigh throughput combinatorial synthesis of discrete compounds in multimilligram quantitiesPositionally addressable parallel synthesis on membrane supportsResins and anchors for solid phase organic synthesisOrganic reactions on solid support - an overviewAnalytical methods in combinatorial chemistryMulti-component reactions (mcrs) of isocyanides and their chemical librariesMulti-step solution phase combinatorial synthesisExperimental techniques in fluorous synthesisDendrimer-supported combinatorial chemistryAutomated solution phase synthesis and its application in combinatorial chemistryCombinatorial discovery and optimization of electrocatalystsCombinatorial library synthesis using polymer-supported catalystsCombinatorial Approaches to chiral catalysts discovery